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临床结核病与治疗结果。

Clinical tuberculosis and treatment outcomes.

机构信息

Tuberculosis Unit, Liverpool Heart and Chest Hospital, Liverpool, UK.

出版信息

Int J Tuberc Lung Dis. 2010 Jun;14(6):683-8.

PMID:20487604
Abstract

The global targets for tuberculosis (TB) control set by the World Health Assembly (WHA) in 1991 were detection of at least 70% and cure of at least 85% of new sputum smear-positive TB cases by 2000, later revised to 2005. The DOTS strategy was introduced in the mid-1990s, and later became the cornerstone of the Stop TB Strategy, which was launched along with the Global Plan to Stop TB 2006-2015 in 2006. The Global Plan sets out how and to what extent the Stop TB Strategy should be implemented between 2006 and 2015 to achieve the TB-related Millennium Development Goal (MDG) to halt and reverse the incidence of TB by 2015 and the Stop TB Partnership targets to reduce TB prevalence and death rates to 50% of 1990 levels by 2015, and to eliminate TB as a public health concern by 2050. Treatment success and case detection rates are outcome indicators used to measure the effectiveness of TB control along with the impact indicators incidence, prevalence and death rates. Globally, the rate of treatment success for smear-positive cases treated exceeded the WHA global target of 85% for the first time in 2007. This review focuses on articles related to treatment outcome in TB published in the International Journal of Tuberculosis and Lung Disease in 2009.

摘要

1991 年世界卫生大会(WHA)为结核病(TB)控制设定了全球目标,即到 2000 年,新涂阳肺结核病例的检出率至少达到 70%,治愈率至少达到 85%,后来修订为 2005 年。DOTS 策略于 20 世纪 90 年代中期推出,后来成为 2006 年启动的《遏制结核病战略》的基石。《全球结核病规划 2006-2015》提出了如何以及在多大程度上实施《遏制结核病战略》,以实现结核病相关千年发展目标(MDG),即到 2015 年遏制和扭转结核病发病率,以及实现 2015 年将结核病发病率和死亡率降低到 1990 年水平的 50%,并在 2050 年消除结核病对公共卫生的威胁。治疗成功率和病例检出率是衡量结核病控制效果的结果指标,与发病率、患病率和死亡率等影响指标一起使用。在全球范围内,2007 年首次实现了涂阳病例治疗成功率超过 WHA 全球 85%的目标。本综述重点介绍了 2009 年《国际结核病和肺部疾病杂志》上发表的与结核病治疗结果相关的文章。

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