结核病应对计划B：是时候认真考虑通风不良的集体场所了。
Plan Beta for tuberculosis: it's time to think seriously about poorly ventilated congregate settings.
作者信息
Yates T A, Tanser F, Abubakar I
机构信息
Centre for Infectious Disease Epidemiology, Research Department of Infection and Population Health, University College London, London, UK; Wellcome Trust Africa Centre for Population Health, University of KwaZulu-Natal, Mtubatuba, South Africa.
Wellcome Trust Africa Centre for Population Health, University of KwaZulu-Natal, Mtubatuba, South Africa; School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.
出版信息
Int J Tuberc Lung Dis. 2016 Jan;20(1):5-10. doi: 10.5588/ijtld.15.0494.
Globally, the rates of decline in tuberculosis (TB) incidence are disappointing, but in line with model predictions regarding the likely impact of the DOTS strategy. Here, we review evidence from basic epidemiology, molecular epidemiology and modelling, all of which suggest that, in high-burden settings, the majority of Mycobacterium tuberculosis transmission may occur in indoor congregate settings. We argue that mass environmental modifications in these places might have a significant impact on TB control and suggest a research agenda that might inform interventions of this nature. The necessary technology exists and, critically, implementation would not be dependent on health care workers who are in short supply in the communities worst affected by TB.
在全球范围内，结核病发病率的下降速度令人失望，但与关于直接督导下的短程化疗（DOTS）策略可能产生的影响的模型预测相符。在此，我们回顾了来自基础流行病学、分子流行病学和模型研究的证据，所有这些证据都表明，在高负担地区，大多数结核分枝杆菌传播可能发生在室内聚集场所。我们认为，对这些场所进行大规模环境改造可能会对结核病控制产生重大影响，并提出了一项研究议程，可为这类干预措施提供参考。必要的技术已经存在，关键的是，实施并不依赖于在受结核病影响最严重的社区中供应短缺的医护人员。
Zotero 插件