Kram H B, Shoemaker W C, Clark S R, Macabee J R, Yamaguchi M A
Department of Surgery, Los Angeles County King/Drew Medical Center, California.
Am Surg. 1991 Jun;57(6):381-4.
In the present report, the authors describe the use of aerosolized fibrin glue (FG) to achieve hemostasis in patients with nonsuturable hemorrhage. The multicomponent FG was sprayed on bleeding tissues with a dual chamber spray head that allowed simultaneous application and mixing of fibrinogen and thrombin on the tissue surface. Sterile propellant gas was passed through tubing to the spray head and independently controlled, allowing for drying of the tissue surface immediately before FG application. This technique was found to be effective in achieving hemostasis of parenchymal organs, retroperitoneal surfaces, and skin graft donor sites. Additional potential applications of this technique include the control of hemorrhage from mediastinal and pleural surfaces.
在本报告中，作者描述了使用雾化纤维蛋白胶（FG）对无法缝合止血的患者进行止血的情况。多组分FG通过双腔喷头喷在出血组织上，该喷头可在组织表面同时施加并混合纤维蛋白原和凝血酶。无菌推进气体通过管道输送到喷头并独立控制，使得在FG施加前能立即干燥组织表面。该技术被发现对实现实质器官、腹膜后表面及皮肤移植供区的止血有效。该技术的其他潜在应用包括控制纵隔和胸膜表面的出血。
