Kırıkkale University, Department of Psychiatry, Süleyman Demirel Research and Education Hospital, Kırıkkale, 71100, Turkey.
Psychiatry Res. 2010 Oct 30;179(3):306-11. doi: 10.1016/j.psychres.2009.04.016. Epub 2010 May 21.
Studies indicate that patients with obsessive-compulsive disorder (OCD) have slowing in cognitive processing, especially in the presence of a conflict. This study aimed to determine whether decision and motor times in OCD patients were affected by manipulating the congruence/incongruence of lexical and prosodic aspects of commands. An experimental paradigm was designed to simulate a situation that can trigger anxiety and obsessions in OCD patients. Commands with or without a conflict, that is, an incongruence between lexical and prosodic aspects, were given to the participants. Decision time, motor time and errors were the main parameters of the experiment. The control group had significantly faster decision times than the OCD group in response to both conflicting and non-conflicting commands. The OCD patients demonstrated higher trait anxiety, while Stroop interference and state anxiety were not significantly different between the groups. These results suggest that OCD patients experience slowing in their response times, regardless of whether the stimuli are conflicting or not.
研究表明，强迫症（OCD）患者的认知加工速度较慢，尤其是在存在冲突的情况下。本研究旨在确定通过操纵词汇和韵律方面的一致性/不一致性来操纵决策和运动时间是否会影响 OCD 患者。设计了一个实验范式来模拟可能引发 OCD 患者焦虑和强迫的情况。向参与者提供有或没有冲突的命令，即词汇和韵律方面的不一致。决策时间、运动时间和错误是实验的主要参数。对照组在对冲突和非冲突命令的反应中，决策时间明显快于 OCD 组。OCD 患者表现出更高的特质焦虑，而 Stroop 干扰和状态焦虑在两组之间没有显著差异。这些结果表明，无论刺激是否存在冲突，OCD 患者的反应时间都会减慢。
