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口咽肿瘤切除及放疗后严重的面颊和下眼睑淋巴水肿。

Severe cheek and lower eyelid lymphedema after resection of oropharyngeal tumor and radiation.

作者信息

Silverman Adam T, Hoffman Ryan, Cohen Mimis, Garza Rebecca

机构信息

University of Illinois Medical Center at Chicago, Illinois 60612, USA.

出版信息

J Craniofac Surg. 2010 Mar;21(2):598-601. doi: 10.1097/SCS.0b013e3181d08c90.

DOI:10.1097/SCS.0b013e3181d08c90
PMID:20489462
Abstract

Facial lymphedema, a rare condition with poorly understood pathogenesis, is commonly associated with previous infection, radiation therapy, local tumor growth, or previous surgery in the head and neck region. Few cases of isolated facial lymphedema have been reported in the literature. Surgical excision has emerged as the mainstay of therapy in such cases, although the long-term efficacy and recurrence rate after excision remain unknown. We present a unique case of a patient with severe unilateral facial lymphedema, which manifested many years after extirpation of a floor-of-the-mouth squamous cell carcinoma, bilateral supraomohyoid neck dissections, and radiation therapy. The massive cheek and eyelid lymphedema, which extended from the patient's left lower eyelid to patient's oral commissure measured 11 x 15 cm with a thickened, brawny, lobulated, and bosselated skin surface. This mass interfered with activities of daily life, caused poor oral intake, and contributed to the patient's severe kyphosis. Because the mass did not clinically or radiologically appear to be malignant, we decided to perform a salvage procedure consisting of wide excision of the massive lymphedematous mass and immediate coverage with a split-thickness skin grafting. Temporary tarsorraphy sutures were also used to provide support to the lower eyelid. The patient tolerated the procedure well, with no complications and with full take of the skin graft. Postoperatively, he was very grateful to be relieved of his debilitating symptoms.

摘要

面部淋巴水肿是一种发病机制鲜为人知的罕见病症,通常与既往感染、放射治疗、局部肿瘤生长或头颈部既往手术有关。文献中报道的孤立性面部淋巴水肿病例很少。手术切除已成为此类病例的主要治疗方法,尽管切除后的长期疗效和复发率尚不清楚。我们报告了一例独特的严重单侧面部淋巴水肿患者,该症状在口底鳞状细胞癌切除、双侧肩胛舌骨上颈清扫术和放射治疗多年后出现。巨大的脸颊和眼睑淋巴水肿从患者左下眼睑延伸至口角,大小为11×15厘米,皮肤表面增厚、坚硬、呈分叶状且有结节状。该肿物干扰了日常生活活动,导致口腔摄入不良,并加重了患者的严重脊柱后凸。由于该肿物在临床和放射学上均未显示为恶性,我们决定实施挽救手术,包括广泛切除巨大的淋巴水肿肿物并立即用中厚皮片覆盖。还使用了临时睑缘缝合术来支撑下眼睑。患者对手术耐受良好,无并发症,皮片完全成活。术后,他对症状得到缓解非常感激。

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