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急性腹痛镇痛中的性别、年龄和种族问题:不同人群的镇痛效果是否一致?

Gender, age and ethnic aspects of analgesia in acute abdominal pain: is analgesia even across the groups?

机构信息

Department of Visceral Surgery and Medicine, Inselspital, Berne University Hospital and University of Berne, Berne, Switzerland.

出版信息

Intern Med J. 2012 Mar;42(3):281-8. doi: 10.1111/j.1445-5994.2010.02255.x. Epub 2010 May 11.

Abstract

BACKGROUND

Numerous studies have shown differences in pain perception between men and women, which may affect pain management strategies.

AIM

Our primary aim was to investigate whether there are gender-based differences in pain management in patients admitted to our emergency department with acute, non-specific abdominal pain (NSAP). Our secondary aim was to evaluate if other factors influence administration of analgesia for patients admitted with NSAP.

METHODS

From June 2007 to June 2008, we carried out a retrospective, gender-based, frequency-matched control study with 150 patients (75 consecutive men and 75 women) who presented with NSAP at our emergency department. Pain was documented using a numerical rating scale ('0' no pain, '10' most severe pain). A multinomial regression model was used to assess factors that might influence pain management.

RESULTS

No statistically significant difference was seen between men and women with respect to pain management (P= 0.085). Younger patients were, however, more likely to receive weaker (P= 0.011) and fewer analgesics (P < 0.001). Patients with previous abdominal surgery (P= 0.012), known chronic pain conditions (P= 0.029) or relevant comorbidities (P= 0.048) received stronger analgesia. Nationality (P= 0.244), employment status (P= 0.988), time of admission (P= 0.487) and known psychiatric illness (P= 0.579) did not influence pain management.

CONCLUSIONS

No statistically significant gender-dependent differences in pain management were observed. However, younger patients received less potent analgesic treatment. There is no reason for certain groups to receive suboptimal treatment, and greater efforts should be made to offer consistent treatment to all patients.

摘要

背景

许多研究表明,男性和女性在疼痛感知方面存在差异,这可能会影响疼痛管理策略。

目的

我们的主要目的是研究在因急性非特异性腹痛(NSAP)而入住我们急诊科的患者中,疼痛管理是否存在基于性别的差异。我们的次要目的是评估其他因素是否会影响因 NSAP 入院患者的镇痛治疗。

方法

从 2007 年 6 月至 2008 年 6 月,我们对 150 例因 NSAP 而入住我们急诊科的患者进行了回顾性、基于性别的、频率匹配对照研究(75 例连续男性患者和 75 例女性患者)。疼痛采用数字评分量表(“0”无疼痛,“10”最严重疼痛)进行记录。采用多项回归模型评估可能影响疼痛管理的因素。

结果

在疼痛管理方面,男性和女性之间没有统计学上的显著差异(P=0.085)。然而,年轻患者更有可能接受较弱的(P=0.011)和较少的镇痛剂(P<0.001)。有腹部手术史(P=0.012)、已知慢性疼痛疾病(P=0.029)或相关合并症(P=0.048)的患者接受了更强的镇痛治疗。国籍(P=0.244)、就业状况(P=0.988)、入院时间(P=0.487)和已知精神疾病(P=0.579)对疼痛管理没有影响。

结论

在疼痛管理方面未观察到统计学上显著的性别依赖性差异。然而,年轻患者接受的镇痛治疗效果较弱。没有理由让某些群体接受不理想的治疗,应做出更大努力为所有患者提供一致的治疗。

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