Department of Plastic Surgery, Helsinki University Hospital, Helsinki, Finland.
Int Wound J. 2010 Aug;7(4):277-81. doi: 10.1111/j.1742-481X.2010.00684.x. Epub 2010 May 18.
The purpose of this study is to review the management and running of the Helsinki Skin Bank between the years 2001 and 2008. Further aims were to assess the microbiological safety of the glycerol-preserved allograft skin and analyse its clinical use. The files of the Helsinki Skin Bank were reviewed for allograft skin harvested from organ donors between 2001 and 2008. Data on harvested skin area and microbiological culture results were collected. The patients receiving allograft were also identified and operation indications analysed. Allograft skin was collected from 115 donors, with a mean of 44,335 cm(2) per year. No skin batches were discarded. Microbiological cultures of the allograft skin batches were negative in 86 (75%) cases. Thirty-five donor skin batches were used in 69 operations. The most common indication was 'Biological dressing on partial-thickness burns', comprising 52% of cases. The cost per cm(2) was 0.81euro. The use of allograft skin in the Helsinki Skin Bank is microbiologically safe and continues to provide a versatile and useful treatment modality in many major burn cases with few observed complications. As compared with synthetically produced temporary dressings currently available, our allograft skin is also more economical.
本研究旨在回顾 2001 年至 2008 年期间赫尔辛基皮肤库的管理和运行情况。进一步的目的是评估甘油保存的同种异体皮的微生物安全性，并分析其临床应用。对 2001 年至 2008 年间从器官捐献者中采集的同种异体皮肤的赫尔辛基皮肤库档案进行了回顾。收集了所采集皮肤面积和微生物培养结果的数据。还确定了接受同种异体皮肤的患者，并分析了手术适应证。从 115 名供体中采集了同种异体皮肤，每年平均采集 44335cm(2)。没有丢弃任何皮肤批次。86 例（75%）同种异体皮肤批次的微生物培养结果为阴性。35 个供体皮肤批次用于 69 例手术。最常见的适应证是“部分厚度烧伤的生物敷料”，占 52%。每平方厘米的成本为 0.81 欧元。赫尔辛基皮肤库中同种异体皮肤的使用在微生物学上是安全的，并且继续为许多大面积烧伤病例提供了一种多功能且有用的治疗方式，观察到的并发症很少。与目前可用的合成临时敷料相比，我们的同种异体皮肤也更经济。
