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取自身体塑形手术的甘油保存全层同种异体皮肤移植的储存与使用。

Banking and use of glycerol preserved full-thickness skin allograft harvested from body contouring procedures.

作者信息

Zidan Serag M, Eleowa Samy A

机构信息

Department of Plastic Surgery and Burn, Faculty of Medicine, Al-Azhar University, Almokhayyam Aldaem Street, Nasr City, Cairo, Egypt.

Department of Plastic Surgery and Burn, Faculty of Medicine, Al-Azhar University, Almokhayyam Aldaem Street, Nasr City, Cairo, Egypt.

出版信息

Burns. 2014 Jun;40(4):641-7. doi: 10.1016/j.burns.2013.08.039. Epub 2013 Sep 23.

DOI:10.1016/j.burns.2013.08.039
PMID:24070848
Abstract

INTRODUCTION

The use of glycerol preserved skin allograft (GPA) became a main stay in burn treatment. However, harvesting of cadaveric skin is not yet legalized in many countries including Egypt.

OBJECTIVES

To estimate the feasibility of using skin harvested from body contouring procedures as a source of GPA and its clinical efficacy.

PATIENTS AND METHODS

Skin harvested from body contouring procedures done in Al-Azhar university hospitals was preserved by glycerolization and used in management of burn and complicated wounds.

RESULTS

In the period between February 2012 and February 2013 skin was harvested from 24 abdomenoplasty cases, 6 bilateral breast reduction cases, and 1 case of thigh lift done in Al-Azhar university hospitals. This yielded about 22,000 cm(2) of skin preserved by glycerolization. This GPA was used in 15 excised burn wounds, in 9 cases of chronic burn wounds, and in 6 complicated wounds. Partial graft loss occurred in 3 cases and total graft loss occurred in 1 case.

CONCLUSION

The glycerolized full-thickness skin harvested from body contouring procedures is clinically effective in burn and wound management. In the presence of regional coordination, it can serve as an abundant source for skin banking in where cadaveric skin use is not legalized.

摘要

引言

甘油保存的同种异体皮肤移植(GPA)的应用已成为烧伤治疗的主要手段。然而,包括埃及在内的许多国家,尸体皮肤的采集尚未合法化。

目的

评估将身体塑形手术中获取的皮肤作为GPA来源的可行性及其临床疗效。

患者与方法

从爱资哈尔大学医院进行的身体塑形手术中获取的皮肤,经甘油处理后保存,并用于烧伤和复杂伤口的治疗。

结果

在2012年2月至2013年2月期间,从爱资哈尔大学医院进行的24例腹壁成形术、6例双侧乳房缩小术和1例大腿提升术中获取了皮肤。经甘油处理后保存的皮肤约为22,000平方厘米。这些GPA用于15例切除的烧伤创面、9例慢性烧伤创面和6例复杂伤口。3例出现部分移植皮片丢失,1例出现完全移植皮片丢失。

结论

从身体塑形手术中获取的经甘油处理的全层皮肤在烧伤和伤口治疗中具有临床疗效。在区域协调的情况下,在尸体皮肤使用未合法化的地区,它可作为皮肤库的丰富来源。

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