Chua Alvin, Song Colin, Chai Andrea, Chan Lennard, Tan Kok Chai
Department of Plastic/Burns Surgery, Singapore General Hospital, Outram Road, S169608 Singapore, Singapore.
Burns. 2004 Nov;30(7):696-700. doi: 10.1016/j.burns.2004.03.016.
The skin banking programme was set-up in Singapore in 1998 to provide a ready source of allografts for patients with severe burns. The process and problems in establishing a local skin bank will be described together with a retrospective review of skin allograft recipients to determine the efficacy of the programme. For the skin bank set-up, pertinent issues related to legislation, methods, logistics, quality assurance and donation rate are discussed. In this retrospective review, a comparison between patients who had early complete excision with skin allograft transplantation and those who received conventional staged excision and coverage, was analysed in terms of clinical profile and outcome using statistical methods. The former group presented a significant reduction of mortality rate and hospital stay by 29% and 10 days, respectively. The establishment of the skin bank has helped in the management of severe burn patients by facilitating early excision and allografting. In a Burn Centre, therefore, it is essential to have an ample supply of skin allograft for burn victims in readiness for mass disaster situations.
新加坡于1998年设立了皮肤库项目，为严重烧伤患者提供现成的同种异体移植皮肤来源。本文将描述建立本地皮肤库的过程和问题，并对皮肤同种异体移植受者进行回顾性分析，以确定该项目的成效。对于皮肤库的建立，将讨论与立法、方法、后勤、质量保证和捐赠率相关的关键问题。在这项回顾性分析中，采用统计方法，对早期进行彻底切除并移植同种异体皮肤的患者与接受传统分期切除和覆盖治疗的患者的临床特征和治疗结果进行了比较。前一组患者的死亡率和住院时间显著降低，分别降低了29%和10天。皮肤库的建立通过促进早期切除和移植，有助于严重烧伤患者的治疗。因此，在烧伤中心，必须为烧伤患者储备充足的同种异体皮肤，以备应对大规模灾难情况。
