细菌感染过程中宿主细胞的翻译后修饰。

Post-translational modifications in host cells during bacterial infection.

机构信息

Institut Pasteur, Unité des Interactions Bactéries-Cellules, Département de Biologie Cellulaire et Infection, Paris, France.

出版信息

FEBS Lett. 2010 Jul 2;584(13):2748-58. doi: 10.1016/j.febslet.2010.05.012. Epub 2010 May 21.

DOI:10.1016/j.febslet.2010.05.012

PMID:20493189

Abstract

Post-translational modification of proteins is a widespread mechanism used by both prokaryotic and eukaryotic cells to modify the activity of key factors that plays fundamental roles in cellular physiology. This review focuses on how bacterial pathogens can interfere with host post-translational modifications to promote their own survival and replication.

摘要

蛋白质的翻译后修饰是原核细胞和真核细胞广泛采用的一种机制，用于修饰在细胞生理学中起基本作用的关键因子的活性。本文重点介绍了细菌病原体如何干扰宿主的翻译后修饰，以促进自身的存活和复制。