Gastroenterology Department, Mersin University Medical Faculty, Mersin, Turkey.
Gastrointest Endosc. 2010 Jul;72(1):198-203. doi: 10.1016/j.gie.2010.02.012. Epub 2010 May 20.
Ectopic opening of the common bile duct (CBD) into the GI tract is an extremely rare congenital anomaly. The clinical implications and frequency of this anomaly are not clearly known.
To present a case series of ectopic opening of the CBD into various sites of the upper digestive tract and discuss clinicopathological features of this condition.
Retrospective, observational study in a single tertiary care medical center.
Consecutive patients undergoing ERCP who received a diagnosis of an ectopic opening of the CBD between September 2001 and August 2009 were reviewed.
Endoscopic and cholangiographic findings were reviewed.
The endoscopic and cholangiographic findings and clinical course of these patients were reviewed.
During the study period, 1040 patients underwent ERCP. A total of 11 patients (6 men and 5 women with a median age of 59.2 years) received a diagnosis of an ectopic opening of the CBD. The opening sites of the CBD were located as follow: 1 in the stomach, 4 in the duodenal bulb, 3 at a more lateral site of the second portion of the duodenum, and 3 in the third part of the duodenum. Seven patients had choledocholithiasis, 2 had acute pancreatitis, and 3 had severe cholangitis.
Although an ectopic opening of the CBD is rare, it may be associated with severe pancreaticobiliary disorders. Endoscopists should be aware of this anomaly and know what to do in case they encounter the condition.
胆总管(CBD)异位开口于胃肠道是一种极其罕见的先天性异常。这种异常的临床意义和频率尚不清楚。
介绍一组 CBD 异位开口于上消化道不同部位的病例系列,并讨论该疾病的临床病理特征。
单中心三级保健机构的回顾性观察性研究。
2001 年 9 月至 2009 年 8 月期间行 ERCP 诊断为 CBD 异位开口的连续患者。
回顾内镜和胆管造影结果。
回顾这些患者的内镜和胆管造影结果及临床过程。
在研究期间,1040 例患者接受了 ERCP。共有 11 例患者(6 名男性和 5 名女性,中位年龄 59.2 岁)诊断为 CBD 异位开口。CBD 的开口部位如下:1 例位于胃,4 例位于十二指肠球部,3 例位于十二指肠第二部分更外侧,3 例位于十二指肠第三部分。7 例患者有胆总管结石,2 例有急性胰腺炎,3 例有严重胆管炎。
尽管 CBD 异位开口罕见,但可能与严重的胰胆管疾病相关。内镜医生应意识到这种异常,并在遇到这种情况时知道该怎么做。