Dr. Lütfi Kirdar Kartal Training and Research Hospital, Istanbul, Turkey.
J Cataract Refract Surg. 2010 Jun;36(6):978-85. doi: 10.1016/j.jcrs.2009.12.031.
To compare the outcomes of implantation of 2 models of intrastromal corneal ring segments (ICRS) to manage keratoconus.
Kartal Training and Research Hospital, Istanbul, Turkey.
This study evaluated eyes with keratoconus that had implantation of Keraring ICRS (Group A) or Intacs ICRS (Group B). The corneal tunnels were created mechanically or with a femtosecond laser. The uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, keratometry (K) readings (Orbscan II), and complications in the 2 groups were compared.
Group A comprised 100 eyes and Group B, 68 eyes. The postoperative increase in UDVA and CDVA was statistically significant in both groups (P<.05). Group A had greater improvement in CDVA than Group B at 6 months and 1 year (both P<.001). At 1 year, the decrease in the mean maximum K power was statistically significant in Group A (51.27 diopters [D] +/- 4.46 [SD] to 47.87 +/- 3.39 D) and in Group B (51.12 +/- 4.54 D to 47.58 +/- 3.66 D) (P<.05). The mean reduction in maximum K was statistically significantly greater in Group A at 6 months and 1 year (P = .018 and P = .024, respectively). There were no statistically significant differences in visual or refractive results between femtosecond laser and mechanical tunnel creation.
Although both ICRS models were effective and safe in managing keratoconus, the Keraring ICRS led to more improvement in CDVA and UDVA and a greater reduction in the maximum K value.
比较两种基质内角膜环段(ICRS)植入物治疗圆锥角膜的效果。
土耳其伊斯坦布尔 Kartal 培训与研究医院。
本研究评估了植入 Keraring ICRS(A 组)或 Intacs ICRS(B 组)的圆锥角膜患者的眼睛。角膜隧道是通过机械或飞秒激光创建的。比较两组的未矫正(UDVA)和矫正(CDVA)远视力、屈光度、角膜曲率(Orbscan II)读数和并发症。
A 组 100 只眼,B 组 68 只眼。两组术后 UDVA 和 CDVA 均有统计学显著提高(均 P<.05)。A 组术后 6 个月和 1 年时 CDVA 改善均大于 B 组(均 P<.001)。1 年后,A 组平均最大 K 力下降有统计学意义(51.27 屈光度[D] +/- 4.46[SD]降至 47.87 +/- 3.39 D)和 B 组(51.12 +/- 4.54 D 降至 47.58 +/- 3.66 D)(均 P<.05)。A 组 6 个月和 1 年时最大 K 降低的平均降幅有统计学显著差异(分别为 P =.018 和 P =.024)。飞秒激光和机械隧道创建在视力和屈光结果方面无统计学显著差异。
虽然两种 ICRS 模型在治疗圆锥角膜方面均有效且安全,但 Keraring ICRS 可使 CDVA 和 UDVA 得到更大改善,并使最大 K 值降低更多。