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深板层角膜移植术与基质内角膜环段植入术治疗晚期圆锥角膜的比较。

Comparison of deep anterior lamellar keratoplasty and intrastromal corneal ring segment implantation in advanced keratoconus.

机构信息

Kartal Training and Research Hospital, Bezmi Alem University, Medical Faculty, Istanbul, Turkey.

出版信息

J Cataract Refract Surg. 2012 Feb;38(2):324-32. doi: 10.1016/j.jcrs.2011.08.033.

DOI:10.1016/j.jcrs.2011.08.033
PMID:22322167
Abstract

PURPOSE

To compare the visual and refractive results in eyes with advanced keratoconus having deep anterior lamellar keratoplasty (DALK) with those having intrastromal corneal ring segment (ICRS) implantation.

SETTING

Dr. Lütfi Kırdar Kartal Training and Research Hospital, Istanbul, Turkey.

DESIGN

Comparative case series.

METHODS

Records of advanced keratoconus patients with a clear central cornea and contact lens intolerance who had DALK or ICRS implantation were reviewed. Preoperatively and after 24 months, the uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, and Orbscan II keratometry (K) readings in the 2 groups were comparable.

RESULTS

The DALK group comprised 36 eyes and the ICRS group, 30 eyes. Both groups had a statistically significant increase in UDVA and CDVA from preoperatively to 24 months postoperatively (P<.001). The DALK group had a statistically significantly greater improvement in UDVA and CDVA than the ICRS group 24 months postoperatively (P<.001). The improvement in spherical equivalent (SE) refractive error, manifest sphere, and manifest cylinder was statistically significant in both groups (P<.001). The mean reduction in SE and manifest cylinder were significantly greater in the DALK group (P<.05). The postoperative reduction in the maximum and minimum K values was statistically significant in both groups (P<.001); the mean reduction in K values was significantly greater in the DALK group (P<.001).

CONCLUSION

Although DALK provided greater improvement in visual acuity and refractive errors in advanced keratoconus cases, ICRS implantation may be an alternative treatment with satisfactory outcomes and less visual impact.

摘要

目的

比较深板层角膜切开术(DALK)与角膜基质环植入术(ICRS)治疗进展性圆锥角膜的视力和屈光结果。

设置

土耳其伊斯坦布尔吕特菲·基达尔·卡尔塔尔培训与研究医院。

设计

对比病例系列。

方法

回顾了有明确中央角膜且不能耐受接触镜的进展性圆锥角膜患者的记录,这些患者接受了 DALK 或 ICRS 植入术。在术前和术后 24 个月,比较两组的未矫正(UDVA)和矫正(CDVA)远视力、屈光度和 Orbscan II 角膜曲率计(K)读数。

结果

DALK 组包括 36 只眼,ICRS 组包括 30 只眼。两组患者的 UDVA 和 CDVA 在术后 24 个月均有显著提高(P<.001)。与 ICRS 组相比,DALK 组术后 24 个月 UDVA 和 CDVA 的改善具有统计学意义(P<.001)。两组的等效球镜(SE)屈光误差、实际球镜和实际柱镜均有显著改善(P<.001)。DALK 组的 SE 和实际柱镜的平均降低量显著更大(P<.05)。两组术后最大和最小 K 值的降低均具有统计学意义(P<.001);DALK 组的 K 值平均降低量显著更大(P<.001)。

结论

尽管 DALK 可使进展性圆锥角膜患者的视力和屈光不正得到更大程度的改善,但 ICRS 植入术可能是一种替代治疗方法,具有满意的效果和较小的视觉影响。

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