Animal Genetic Resources Laboratory, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.
J Hered. 2010 Sep-Oct;101(5):639-43. doi: 10.1093/jhered/esq047. Epub 2010 May 23.
Y chromosome acts as a single nonrecombining unit that is male specific and in effect haploid, thus ensuring the preservation of mutational events as a single haplotype via male lines. In this study, 6 Y chromosome-specific microsatellites (SSR) were tested for the patrilineal genetic variations of 573 male samples from Chinese domestic horse (30 breeds), Przewalski's horse, and donkey. All the 6 loci appeared as a haplotype block in Przewalski's horse and the domestic donkey. There were notable differences, however, at Y chromosome markers between horse and donkey. There were 2 haplotypes of Eca.YA16 in the domestic horse breeds, Haplotype A (Allele A: 156 bp) and Haplotype B (Allele B: 152 bp). Allele A was the common allele among 30 horse breeds, and Allele B was found in 11 horse breeds. This is the first description of a Y chromosome variant for horses. The 2 haplotypes of Y chromosome discovered in the domestic horse breeds in China could be helpful in unveiling their intricate genetic genealogy.
Y 染色体作为一个单一的非重组单位，是雄性特有的，实际上是单倍体，因此通过雄性系确保突变事件作为单一单倍型得以保存。在这项研究中，对来自中国本地马（30 个品种）、普氏野马和驴的 573 个雄性样本的 Y 染色体特异性微卫星（SSR）进行了 6 个 Y 染色体特异性微卫星（SSR）的亲缘遗传变异测试。在普氏野马和本地驴中，所有 6 个位点都表现为单倍型块。然而，马和驴之间在 Y 染色体标记上存在显著差异。在本地马品种中发现了 2 种 Eca.YA16 单倍型，单倍型 A（等位基因 A：156bp）和单倍型 B（等位基因 B：152bp）。等位基因 A 是 30 个马品种中的常见等位基因，而等位基因 B 则存在于 11 个马品种中。这是对马的 Y 染色体变异的首次描述。在中国本地马品种中发现的 2 种 Y 染色体单倍型有助于揭示其复杂的遗传家谱。
