Peninsula Medical School, University of Exeter, Exeter, EX2 4SG, UK.
Clin Otolaryngol. 2010 Apr;35(2):87-96. doi: 10.1111/j.1749-4486.2010.02098.x.
In the UK approximately 3% of over 50 years olds and 8% of over 70 year olds have severe (794-94 dBHL) to deafness. As deafness increased, hearing aids become increasingly ineffective. Cochelear implants can provide an alternative treatment.
To bring together the research evidence through the robustness of a systematic review of the effectiveness of unilateral cochlear implants for adults. We also sought to systematically review the published literature on cost-effectiveness. TYPES OF REVIEW: Systematic review.
This examined 16 electronic databases, plus bibliographies and references for published and unpublished studies from inception to june 2009.
Abstracts were independently assessed against inclusion criteria by two researchers were compared and disagreements resolved. Included papers were then retrieved and further independently assessed in a similar way. Remaining studies had their data independently extracted by one of five reviewers and checked by another reviewer.
From 1,580 titles and abstracts nine studies were included. These were of variable quality; some study's results should be viewed with caution. The studies were too hetrogeneous to pool the data. However, overall the results firmly supported the use of unilateral cochler implants for severe to profoundly deaf adults. Additionally, four UK based economic evaluations found unilateral cochlear implants to be cost-effectivene in adults at UK implants centres.
The methodologically weak but universally positive body of effectiveness evidence supports the use of unilateral cochlear implants in adults. Previous economic evaluations indicate that such implants are likely to be cost-effective.
在英国，约有 3%的 50 岁以上人群和 8%的 70 岁以上人群患有严重（794-94dBHL）至耳聋。随着耳聋程度的增加，助听器的效果越来越差。人工耳蜗植入物可以提供一种替代治疗方法。
通过对单侧人工耳蜗植入物对成人有效性的系统综述，汇集研究证据。我们还旨在系统地综述已发表的关于成本效益的文献。
系统综述。
该研究共检索了 16 个电子数据库，并查阅了截至 2009 年 6 月的已发表和未发表研究的参考文献和参考文献。
两名研究人员独立评估摘要是否符合纳入标准，并对结果进行比较，解决分歧。然后检索纳入的论文，并以类似的方式进一步独立评估。其余研究的数据由五名评审员中的一名独立提取，并由另一名评审员检查。
从 1580 个标题和摘要中，有 9 项研究符合纳入标准。这些研究的质量参差不齐；一些研究的结果应谨慎看待。这些研究太异质化，无法对数据进行汇总。然而，总体而言，研究结果有力地支持了单侧人工耳蜗植入物在严重至极重度耳聋成人中的应用。此外，四项英国经济评估发现，在英国植入中心，单侧人工耳蜗植入在成人中具有成本效益。
虽然方法学上较为薄弱，但普遍积极的有效性证据支持在成人中使用单侧人工耳蜗植入物。先前的经济评估表明，此类植入物可能具有成本效益。
