Department of Medical Oncology, Azienda University Hospital, University of Cagliari, Cagliari, Italy.
Cancer. 2010 Jun 1;116(11 Suppl):2736-40. doi: 10.1002/cncr.25164.
Breast cancer represents the most common cancer among women in Italy. In the last decade, an increase in incidence and a decrease in mortality from breast cancer have been observed in Italy. These findings may be explained at least in part by the implementation of organized screening programs (SMPs). The screening programs are not diffused homogeneously throughout Italy, where approximately 60% of the population in covered, which explains in part the different outcomes observed across Italy. On the basis of the available data, the authors of this report performed a retrospective analysis on the incidence of 2 different groups of breast cancer patients: those covered or and those not covered by SMPs in Italy. The rates of incidence of T4a, T4b, and T4c breast cancer and of T4 inflammatory breast cancer (IBC) overtime appeared to be lower for the population that was covered by SMPs. On the basis of the estimated 40,000 new cases of breast cancer in Italy per year, the authors attempted to extrapolate the approximate incidence of new cases of T4 breast cancer and calculated that there were between 2800 and 3600 new cases per year taking into account the differences in incidence observed in areas covered or not covered by SMPs. Following the same extrapolations, the estimated incidence of IBC was approximately 200 to 800 new cases per year, representing from 0.6% to 2% of all breast cancers diagnosed every year in Italy.
在意大利，乳腺癌是女性最常见的癌症。在过去的十年中，意大利的乳腺癌发病率有所上升，死亡率有所下降。这些发现至少可以部分解释为实施了有组织的筛查计划（SMPs）。筛查计划在意大利并没有均匀普及，大约有 60%的人口在覆盖范围内，这部分解释了意大利各地不同的结果。基于现有的数据，本报告的作者对两组不同的乳腺癌患者的发病率进行了回顾性分析：一组是覆盖范围内的患者，另一组是未覆盖 SMPs 的患者。随着时间的推移，T4a、T4b 和 T4c 乳腺癌和 T4 炎性乳腺癌（IBC）的发病率似乎较低。基于意大利每年估计有 4 万例新的乳腺癌病例，作者试图推断出 T4 乳腺癌新发病例的近似发病率，并计算出每年考虑到 SMPs 覆盖或未覆盖地区观察到的发病率差异，新发病例约为 2800 至 3600 例。根据相同的推断，IBC 的估计发病率约为每年 200 至 800 例新发病例，占意大利每年诊断的所有乳腺癌的 0.6%至 2%。
