新加坡不同种族人群的载脂蛋白A-IV多态性
Apolipoprotein A-IV polymorphism in Singapore ethnic groups.
作者信息
Saha N
机构信息
Department of Paediatrics, National University of Singapore.
出版信息
Hum Hered. 1991;41(1):47-52. doi: 10.1159/000153973.
A total of 627 subjects comprising 455 Chinese, 127 Dravidian Indians and 45 Malays were investigated for serum Apo A-IV polymorphism. The frequency of Apo A-IV2 was found to be significantly higher (p less than 0.001) in Indians (0.043) compared to that in the Chinese (0.010) and Malays (0.011). The frequency of A-IV3 was found to be around 0.02 in all the ethnic groups. A low frequency of A-IV*4 (less than 0.01) was observed in the Chinese and Indians. The phenotypic distribution of Apo A-IV was at Hardy-Weinberg equilibrium in the three ethnic groups.
对总共627名受试者进行了血清载脂蛋白A-IV多态性研究，其中包括455名中国人、127名达罗毗荼印度人和45名马来人。结果发现，印度人（0.043）的载脂蛋白A-IV2频率显著高于中国人（0.010）和马来人（0.011）（p<0.001）。在所有种族群体中，A-IV3的频率约为0.02。在中国人和印度人中观察到A-IV*4的频率较低（<0.01）。载脂蛋白A-IV的表型分布在这三个种族群体中处于哈迪-温伯格平衡状态。
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