采用糖化血红蛋白定义美国成年人的代谢综合征。

Using glycosylated hemoglobin to define the metabolic syndrome in United States adults.

机构信息

Department of Medicine, University of Hong Kong, Hong Kong, China.

出版信息

Diabetes Care. 2010 Aug;33(8):1856-8. doi: 10.2337/dc10-0190. Epub 2010 May 26.

DOI:10.2337/dc10-0190

PMID:20504895

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2909078/

Abstract

OBJECTIVE

To compare the use of GHb and fasting plasma glucose (FPG) to define the metabolic syndrome (MetS).

RESEARCH DESIGN AND METHODS

Data from the U.S. National Health and Nutrition Examination Survey 1999-2006 were used. MetS was defined using the consensus criteria in 2009. Raised blood glucose was defined as either FPG >or=100 mg/dl (5.6 mmol/l) or GHb >or=5.7%.

RESULTS

In 2003-2006, there was 91.3% agreement between GHb and FPG when either was used to define MetS. The agreement was good irrespective of age, sex, race/ethnicity, BMI, and diabetes status (>or=87.4%). Similar results were found in 1999-2002. Among subjects without diabetes, only the use of GHb alone, but not FPG, resulted in significant association with cardiovascular diseases (odds ratio 1.45, P = 0.005).

CONCLUSIONS

Using GHb instead of FPG to define MetS is feasible. It also identifies individuals with increased cardiovascular risk.

摘要

目的

比较使用糖化血红蛋白（GHb）和空腹血糖（FPG）来定义代谢综合征（MetS）。

研究设计和方法

使用了美国国家健康和营养调查 1999-2006 年的数据。MetS 采用 2009 年的共识标准进行定义。升高的血糖定义为 FPG>或=100mg/dl（5.6mmol/l）或 GHb>或=5.7%。

结果

在 2003-2006 年，当使用 GHb 或 FPG 定义 MetS 时，两者之间有 91.3%的一致性。无论年龄、性别、种族/民族、BMI 和糖尿病状况（≥87.4%）如何，这种一致性都很好。在 1999-2002 年也发现了类似的结果。在没有糖尿病的受试者中，只有单独使用 GHb，而不是 FPG，与心血管疾病显著相关（比值比 1.45，P=0.005）。

结论

使用 GHb 替代 FPG 来定义 MetS 是可行的。它还可以识别出心血管风险增加的个体。

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采用糖化血红蛋白定义美国成年人的代谢综合征。

Using glycosylated hemoglobin to define the metabolic syndrome in United States adults.

机构信息

Department of Medicine, University of Hong Kong, Hong Kong, China.

出版信息

Diabetes Care. 2010 Aug;33(8):1856-8. doi: 10.2337/dc10-0190. Epub 2010 May 26.

DOI:10.2337/dc10-0190

PMID:20504895

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2909078/

Abstract

OBJECTIVE

To compare the use of GHb and fasting plasma glucose (FPG) to define the metabolic syndrome (MetS).

RESEARCH DESIGN AND METHODS

RESULTS

CONCLUSIONS

Using GHb instead of FPG to define MetS is feasible. It also identifies individuals with increased cardiovascular risk.

摘要

目的

比较使用糖化血红蛋白（GHb）和空腹血糖（FPG）来定义代谢综合征（MetS）。

研究设计和方法

使用了美国国家健康和营养调查 1999-2006 年的数据。MetS 采用 2009 年的共识标准进行定义。升高的血糖定义为 FPG>或=100mg/dl（5.6mmol/l）或 GHb>或=5.7%。

结果

结论

使用 GHb 替代 FPG 来定义 MetS 是可行的。它还可以识别出心血管风险增加的个体。

采用糖化血红蛋白定义美国成年人的代谢综合征。

Using glycosylated hemoglobin to define the metabolic syndrome in United States adults.

机构信息

出版信息

OBJECTIVE

RESEARCH DESIGN AND METHODS

RESULTS

CONCLUSIONS

目的

研究设计和方法

结果

结论

相似文献

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采用糖化血红蛋白定义美国成年人的代谢综合征。

Using glycosylated hemoglobin to define the metabolic syndrome in United States adults.

机构信息

出版信息

OBJECTIVE

RESEARCH DESIGN AND METHODS

RESULTS

CONCLUSIONS

目的

研究设计和方法

结果

结论