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下肢注射肉毒杆菌毒素后痉挛型脑瘫患儿的上肢功能和职业表现

Upper extremity function and occupational performance in children with spastic cerebral palsy following lower extremity botulinum toxin injections.

作者信息

Keren-Capelovitch Tal, Jarus Tal, Fattal-Valevski Aviva

机构信息

Department of Occupational Therapy, Stanley Steyer School of Health Professions, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

出版信息

J Child Neurol. 2010 Jun;25(6):694-700. doi: 10.1177/0883073809344621.

DOI:10.1177/0883073809344621
PMID:20508235
Abstract

We studied the effect of botulinum toxin A injections to the lower extremities of spastic cerebral palsy children on upper limb body function and occupational performance. A total of 16 children with spastic cerebral palsy, aged 2 to 8 years, Gross Motor Function Classification System levels I-IV, referred to a child neurology outpatient clinic for botulinum toxin A injections to the lower limbs, underwent 4 assessments: 1 month prior to injection, immediate pre injection, and at 1 and 5 to 6 months post injection. Three tools were used to test everyday function (Canadian Occupational Performance Measure and the Pediatric Evaluation of Disability Inventory) and upper extremity body function (Quality of Upper Extremity Skills Test). Significant improvement was documented between the immediate preinjection and the 2 postinjection assessments, indicating that improvement lasted for at least 6 months. Botulinum toxin A injections to the lower extremities in children with cerebral palsy improve upper limb body function and occupational performance.

摘要

我们研究了向痉挛型脑瘫儿童下肢注射A型肉毒杆菌毒素对上肢身体功能和职业表现的影响。共有16名年龄在2至8岁、粗大运动功能分类系统为I-IV级的痉挛型脑瘫儿童,因下肢注射A型肉毒杆菌毒素而被转诊至儿童神经科门诊,他们接受了4次评估:注射前1个月、即将注射前、注射后1个月以及注射后5至6个月。使用了三种工具来测试日常功能(加拿大职业表现测量量表和儿童残疾评估量表)和上肢身体功能(上肢技能测试质量)。在即将注射前和两次注射后评估之间记录到了显著改善,表明改善持续了至少6个月。向脑瘫儿童下肢注射A型肉毒杆菌毒素可改善上肢身体功能和职业表现。

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