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残余前列腺的组织形态学和生化研究结果(III):经耻骨后前列腺腺瘤切除术治疗良性前列腺增生后(检测不到的)前列腺特异性抗原维持情况

Histo-morpho-biochemical findings of the residual prostate (III): (undetectable) PSA maintained after retropubic adenomectomy for BPH.

作者信息

Ballesteros Sampol Juan José, Gimeno Beltrán Javier, Fumadó Ciutat Lluís

机构信息

Department of Urology, UQTR and Pathology IMAS Hospitals, Instituto Municipal de Asistencia Sanitaria, Nuestra Señora de la Esperanza Hospital and Nuestra Señora del Mar Hospital, Barcelona, Spain.

出版信息

Arch Esp Urol. 2010 May;63(4):282-6.

Abstract

SUMMARY OBJECTIVES

To present 4 cases with "undetectable" PSA levels (PSA <0.15 ng/ml) long-term postoperative follow-up after retropubic adenomectomy for BPH METHODS: They come from a series of 70 consecutive cases of retropubic prostatic adenomectomies, monitored and controlled at the hospital in their biochemical, histological and morphometric analysis for 5 years following the intervention.

RESULTS

Four patients have demonstrated PSA levels <0.15 in all controls after surgery. Mean follow-up of the global series: 45.25 months. There is correlation between this determination and histological and morphometric data, when they were achieved.

CONCLUSIONS

"Undetectable" PSA after open prostatic adenomectomy could be an equivalent to the expression of "radical cure"of BPH, and a reliable marker for monitoring neo-hyperplasia.

摘要

摘要目的

呈现4例耻骨后前列腺腺瘤切除术后PSA水平“检测不到”(PSA<0.15 ng/ml)的病例,并对其进行长期术后随访 方法:他们来自连续70例耻骨后前列腺腺瘤切除术病例系列,在干预后5年对其进行生化、组织学和形态学分析的监测与控制。

结果

4例患者术后所有检查中PSA水平均<0.15。整个系列的平均随访时间:45.25个月。当获得组织学和形态学数据时,该测定与这些数据之间存在相关性。

结论

开放性前列腺腺瘤切除术后“检测不到”的PSA可能等同于良性前列腺增生“根治”的表达,是监测新增生的可靠标志物。

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