Alunni-Perret Veronique, Vandenbos Fanny, Kechkekian Aurore, Marty Pierre, Legros Fabrice, Michiels Jean François, Cardot-Leccia Nathalie, Fortineau Nicolas, Durant Jacques, Quatrehomme Gérald
Laboratoire de Médecine légale et Anthropologie médico légale, Faculté de médecine (Université de Nice Sophia Antipolis), Nice cedex 2, France.
Am J Forensic Med Pathol. 2010 Sep;31(3):269-72. doi: 10.1097/PAF.0b013e3181e2efe4.
We report on the case of a French citizen who was found dead in his home, 4 days after returning from Cameroon. The patient died of imported malaria, as revealed by the postmortem investigations. Few such cases have been reported throughout the world. This article reviews deaths due to malaria diagnosed at the time of autopsy in France between 1995 and 2005. We conclude that the nonspecific symptoms of malaria can lead to a misdiagnosis and the need for a forensic expert to intervene at the scene of death, which usually occurs in the home. We will remind forensic pathologists of the clinical, biologic, and forensic aspects of this infectious disease. In particular, the uses of microbiologic analyses, the QBC malaria test and the Core malaria Pan/Pv/pf test as well as brain tissue histology will be reviewed.
我们报告了一例法国公民的病例，该公民从喀麦隆回国4天后被发现死于家中。尸检调查显示，该患者死于输入性疟疾。全球范围内报告的此类病例很少。本文回顾了1995年至2005年间在法国尸检时诊断出的疟疾死亡病例。我们得出结论，疟疾的非特异性症状可能导致误诊，并且需要法医专家在通常发生于家中的死亡现场进行干预。我们将提醒法医病理学家注意这种传染病的临床、生物学和法医方面的情况。特别是，将对微生物分析、QBC疟疾检测和Core疟疾全/间日疟原虫/恶性疟原虫检测以及脑组织组织学的应用进行回顾。
