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Osler-Weber-Rendu (OWR) Disease and Heart Failure.奥斯勒-韦伯-伦杜(OWR)病与心力衰竭。
Clin Med Cardiol. 2009 Nov 25;3:121-3. doi: 10.4137/cmc.s3636.
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[Brain abscess and Osler-Weber-Rendu syndrome: Do not forget to look for pulmonary arteriovenous malformations].[脑脓肿与奥斯勒-韦伯-伦杜综合征:别忘了排查肺动静脉畸形]
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Anesthetic management of a patient with Osler-Weber-Rendu syndrome with multiple pulmonary arteriovenous malformations and pheochromocytoma for femoral artificial bone replacement: a case report.奥-韦-伦综合征合并多发肺动静脉畸形和嗜铬细胞瘤患者行股骨人工骨置换术的麻醉管理:1例报告
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Osler-Weber-Rendu disease presenting as recurrent portosystemic encephalopathy in a 75-year-old female patient.一名75岁女性患者以反复发生的门体性脑病为表现的奥斯勒-韦伯-伦迪病
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An Unusual Cause of Right Heart Dysfunction and High Output Heart Failure in a Young Woman.一名年轻女性右心功能不全和高输出量心力衰竭的罕见病因
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Cardiac and Hemodynamic Manifestations of Hereditary Hemorrhagic Telangiectasia.遗传性出血性毛细血管扩张症的心脏和血流动力学表现
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Mutations in the ENG, ACVRL1, and SMAD4 genes and clinical manifestations of hereditary haemorrhagic telangiectasia: experience from the Center for Osler's Disease, Uppsala University Hospital.ENG、ACVRL1 和 SMAD4 基因突变与遗传性出血性毛细血管扩张症的临床表现:来自乌普萨拉大学医院奥尔斯勒病中心的经验。
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High-Output Cardiac Failure Due to Hereditary Hemorrhagic Telangiectasia: A Case of an Extra-Cardiac Left to Right Shunt.遗传性出血性毛细血管扩张症所致高输出量心力衰竭:一例心外左向右分流病例
Int J Angiol. 2017 Jun;26(2):125-129. doi: 10.1055/s-0035-1568878. Epub 2016 Jun 2.
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Combination treatment with an erythropoiesis-stimulating agent and intravenous iron alleviates anaemia in patients with hereditary haemorrhagic telangiectasia.促红细胞生成素刺激剂与静脉铁剂联合治疗可缓解遗传性出血性毛细血管扩张症患者的贫血症状。
Ups J Med Sci. 2014 Nov;119(4):350-3. doi: 10.3109/03009734.2014.955619. Epub 2014 Sep 4.
6
Two cases of high output heart failure caused by hereditary hemorrhagic telangiectasia.两例遗传性出血性毛细血管扩张症所致高输出量心力衰竭。
Korean Circ J. 2012 Dec;42(12):861-5. doi: 10.4070/kcj.2012.42.12.861. Epub 2012 Dec 31.

本文引用的文献

1
High output heart failure.高输出量心力衰竭
QJM. 2009 Apr;102(4):235-41. doi: 10.1093/qjmed/hcn147. Epub 2008 Nov 5.
2
Patients with hereditary hemorrhagic telangiectasia have increased plasma levels of vascular endothelial growth factor and transforming growth factor-beta1 as well as high ALK1 tissue expression.遗传性出血性毛细血管扩张症患者的血浆血管内皮生长因子和转化生长因子-β1水平升高,且ALK1组织表达较高。
Haematologica. 2005 Jun;90(6):818-28.
3
Potential role of modifier genes influencing transforming growth factor-beta1 levels in the development of vascular defects in endoglin heterozygous mice with hereditary hemorrhagic telangiectasia.修饰基因对遗传性出血性毛细血管扩张症内皮糖蛋白杂合小鼠血管缺陷发育过程中转化生长因子-β1水平的潜在影响
Am J Pathol. 2001 Jun;158(6):2011-20. doi: 10.1016/s0002-9440(10)64673-1.

奥斯勒-韦伯-伦杜(OWR)病与心力衰竭。

Osler-Weber-Rendu (OWR) Disease and Heart Failure.

作者信息

Blum Arnon, Shalabi Rafea

机构信息

Department of Medicine, Baruch-Padeh Poria Medical Center, Lower Galilee Israel.

出版信息

Clin Med Cardiol. 2009 Nov 25;3:121-3. doi: 10.4137/cmc.s3636.

DOI:10.4137/cmc.s3636
PMID:20508772
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2872581/
Abstract

OWR is a genetic disease, transmitted as an autosomal dominant disorder characterized by arteriovenous malformations predominantly involving the mucocutaneous epithelium. One of the significant complications is the development of arteriovenous fistulas in different organs like the liver and brain. One of the rarest complications of this arteriovenous conduit is a high-output heart failure. We would like to describe a 66 years old woman who was admitted with a high-output cardiac failure who deteriorated clinically and was treated successfully by conservative management.

摘要

OWR是一种遗传性疾病,以常染色体显性疾病形式传播,其特征是动静脉畸形主要累及黏膜皮肤上皮。其中一个重要并发症是在肝脏和大脑等不同器官形成动静脉瘘。这种动静脉通道最罕见的并发症之一是高输出量心力衰竭。我们想描述一位66岁因高输出量心力衰竭入院的女性患者,其临床症状恶化,经保守治疗成功治愈。