Wei Wen, Liu Sheng-yuan, Zeng Fang-fang, Yao Song-po, Zhang Hai-tao, Wan Gang, Zhong Min, Wang Bin-you
Department of Epidemiology, School of Public Health, Harbin Medical University, Harbin 150086, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Mar;31(3):251-5.
To determine the prevalence and distribution of type 2 diabetes mellitus (T2DM) and the relationship between maximum body mass index (MAXBMI) and T2DM.
From June to August, 2005, a stratified cluster sampling of 1071 permanent residents in communities, over 20 years old, from 4 districts and 1 county of Mudanjiang was chosen. The prevalence of T2DM, and the association between T2DM and different levels of the MAXBMI, current BMI were studied.
The prevalence in the communities was 7.09% and in those with past maximum BMI >/= 28 kg/m(2), it was 12.10%. With the increase of past MAXBMI levels, the risk of T2DM patients also increased significantly (trend chi(2) = 17.387 23, P < 0.0001). Data from multifactor analysis showed that MAXBMI in the past was positively related to T2DM (OR = 3.06, P = 0.0013). In T2DM patients, the group with MAXBMI >/= 27.4 kg/m(2) had higher 2-hour postprandial blood glucose than those with lower MAXBMI (P = 0.0408). When compared with low maximum BMI group in normal blood glucose population, the group with higher MAXBMI (>/= 25.4 kg/m(2)) had higher blood glucose and greater change of BMI.
In both groups that patients with T2DM and with normal glucose, in order to control blood glucose better, researchers should not only concern about the influence of the MAXBMI in the past, but also pay attention to constantly keep BMI at the normal range.
确定2型糖尿病（T2DM）的患病率及分布情况，以及最大体重指数（MAXBMI）与T2DM之间的关系。
2005年6月至8月，采用分层整群抽样法，选取牡丹江市4个区1个县20岁以上的1071名社区常住人口。研究T2DM的患病率，以及T2DM与不同水平的MAXBMI、当前体重指数（BMI）之间的关联。
社区患病率为7.09%，既往最大BMI≥28kg/m²者患病率为12.10%。随着既往MAXBMI水平的升高，T2DM患者的患病风险也显著增加（趋势χ²=17.387 23，P<0.0001）。多因素分析数据显示，既往MAXBMI与T2DM呈正相关（OR=3.06，P=0.0013）。在T2DM患者中，MAXBMI≥27.4kg/m²组的餐后2小时血糖高于MAXBMI较低组（P=0.0408）。与血糖正常人群中MAXBMI较低组相比，MAXBMI较高（≥25.4kg/m²）组的血糖更高，BMI变化更大。
在T2DM患者和血糖正常的两组人群中，为更好地控制血糖，研究人员不仅应关注既往MAXBMI的影响，还应注意持续将BMI维持在正常范围。
