Zhao Ming-hui, Wang Jian-hua, Zhi Xin-yue, Zhu Hong, Liu Xin-min
Department of Epidemiology, School of Public Health, Tianjin Medical University, Tianjin 300070, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2010 Oct;31(10):1130-4.
To investigate the type 2 diabetes mellitus (T2DM) prevalence and related risk factors in adult population with obesity in Tianjin.
With stratified cluster randomized sampling, 2888 obese people with BMI ≥ 28 kg/m(2), aged 18 years old and over were selected from three urban and three rural regions of Tianjin, in 2006. Information on risk factors was collected with questionnaire through face-to-face interview by trained workers and data on fasting blood glucose (FBG) was collected at the same time. 2hrPPG was tested among the people who's FBG ≥ 6.1 mmol/L at the hospital. Prevalence of T2DM was calculated and the distribution of T2DM in the described subgroups and the risk factors analyzed with SPSS software.
The prevalence of T2DM in adult population with obesity was 11.74%, with females (13.90%) higher than males (8.75%). The prevalence rates of T2DM were statistically different among different groups, classified by age, education, occupation, district and BMI. Results from the univariate and multivariate logistic regression analysis showed that the risk factors of T2DM were age (OR = 1.383, 95%CI: 1.254 - 1.525) and sex (OR = 1.591, 95%CI: 1.230 - 2.059) while the protective factor was fruit intake (OR = 0.867, 95%CI: 0.774 - 0.971).
The prevalence of T2DM in adult with obesity was considered to be high. The distribution of T2DM in different subgroups and affecting factors of T2DM in obese adults were different from general population.
调查天津市成年肥胖人群2型糖尿病（T2DM）的患病率及相关危险因素。
2006年采用分层整群随机抽样方法，从天津市3个城区和3个农村地区选取2888名BMI≥28kg/m²、年龄在18岁及以上的肥胖者。由经过培训的工作人员通过面对面访谈采用问卷收集危险因素信息，同时收集空腹血糖（FBG）数据。对FBG≥6.1mmol/L者在医院进行口服葡萄糖耐量试验（OGTT）测定餐后2小时血糖（2hrPPG）。计算T2DM患病率，并用SPSS软件分析T2DM在所描述亚组中的分布情况及危险因素。
成年肥胖人群中T2DM患病率为11.74%，女性（13.90%）高于男性（8.75%）。按年龄、文化程度、职业、地区和BMI分类，不同组间T2DM患病率差异有统计学意义。单因素和多因素logistic回归分析结果显示，T2DM的危险因素为年龄（OR=1.383，95%CI：1.254 - 1.525）和性别（OR=1.591，95%CI：1.230 - 2.059），而保护因素为水果摄入量（OR=0.867，95%CI：0.774 - 0.971）。
成年肥胖人群中T2DM患病率较高。肥胖成年人中T2DM在不同亚组的分布情况及影响因素与一般人群不同。
