瘙痒的创新管理。

Innovative management of pruritus.

机构信息

Department of Dermatology, University of California at San Francisco, 1701 Divisadero Street, 3rd floor, San Francisco, CA 94115, USA.

出版信息

Dermatol Clin. 2010 Jul;28(3):467-78. doi: 10.1016/j.det.2010.03.004.

DOI:10.1016/j.det.2010.03.004

PMID:20510757

Abstract

Pruritus remains a significant problem facing dermatologists and can be associated with various dermatoses and systemic derangements. At times, one can treat the underlying cutaneous or systemic process to alleviate itch. However, it is frequently challenging to identify the cause of a patient's itch and, in this situation, even more difficult to manage the symptom effectively. In this article, the authors discuss the approach to a patient with generalized pruritus without clinically obvious dermatoses. They also addresses mechanisms and management modalities of itch in common systemic diseases, including cholestasis, uremia, and neuropathic dysfunction.

摘要

瘙痒仍然是皮肤科医生面临的一个重大问题，可与各种皮肤疾病和全身性紊乱有关。有时，可以治疗潜在的皮肤或全身性疾病来缓解瘙痒。然而，确定患者瘙痒的原因通常具有挑战性，在这种情况下，更难以有效地控制症状。本文作者讨论了患有无明显临床皮肤病的全身性瘙痒患者的处理方法。他们还讨论了常见全身性疾病（包括胆汁淤积、尿毒症和神经功能障碍）中瘙痒的机制和治疗方法。