Macedo Cristiane Rufino, Atallah Alvaro Nagib
Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, Brazil.
Sao Paulo Med J. 2009 Nov;127(6):346-9. doi: 10.1590/s1516-31802009000600005.
Guidelines are suggestions for clinical practice based on the best available scientific evidence. Nevertheless, in drafting such guidelines, existing systematic reviews are often ignored and are replaced by general consensuses. This ends up compromising the quality of the instructions through bias. Our objective was to investigate whether Cochrane systematic reviews were present among the bibliographic references of prevention and treatment guidelines for dentistry that have been published in databases.
This retrospective, observational study was conducted at the Brazilian Cochrane Center.
The databases were searched for guidelines. Any guidelines obtained were then checked to find whether Cochrane systematic reviews were present in the bibliographic references of the guidelines. In their absence, we checked whether such reviews had not been included because no reviews existed yet, or because such reviews had not been consulted despite already existing.
223 studies were initially selected; of these, 77 were excluded. Of the 146 guidelines included, 46 could have made reference to existing systematic reviews, but only 13 studies did so. Among these 13 studies, eight were systematic reviews following Cochrane methodology. Thirty-three guidelines had not been drafted using published systematic reviews as references, and 100 guidelines had been unable to use Cochrane references because no reviews existed yet.
It is necessary to increase awareness of the importance of using systematic reviews in drafting dentistry guidelines. Likewise, it is necessary to develop systematic reviews that answer questions on the various topics that remain unanswered.
临床实践指南是基于现有最佳科学证据给出的建议。然而,在制定此类指南时,现有的系统评价常常被忽视,取而代之的是一般共识。这最终会因偏差而损害指南的质量。我们的目的是调查在数据库中已发表的牙科预防和治疗指南的参考文献中是否存在Cochrane系统评价。
这项回顾性观察研究在巴西Cochrane中心进行。
在数据库中检索指南。然后检查所获得的任何指南,以确定其参考文献中是否存在Cochrane系统评价。若不存在,我们检查是因为尚无此类评价,还是尽管已有此类评价但未被参考。
最初选定223项研究;其中77项被排除。在纳入的146项指南中,46项本可参考现有系统评价,但只有13项这样做了。在这13项研究中,8项是遵循Cochrane方法的系统评价。33项指南在起草时未以已发表的系统评价为参考文献,100项指南因尚无相关评价而无法使用Cochrane参考文献。
有必要提高对在起草牙科指南时使用系统评价重要性的认识。同样,有必要开展系统评价,以回答各类尚未解决的问题。