Furuse M, Kimura C, Takahashi H, Okumura J
Laboratory of Animal Nutrition, School of Agriculture, Nagoya University, Japan.
J Nutr. 1991 Jul;121(7):1135-8. doi: 10.1093/jn/121.7.1135.
The effect of dietary sorbose on the prevention of the incidence of diabetes in the nonobese diabetic mouse was investigated in animals from 5 to 11 wk of age. When sucrose (200 g/kg diet) in the control diet was replaced by sorbose, body weight was significantly reduced. The blood glucose level also was lowered in mice fed sorbose, but the serum insulin level was unchanged. Glucose was not detected in the urine of mice fed the sorbose diet during the experiment, but some mice in the control group excreted glucose in urine. Relative weights of the heart, liver and left kidney were significantly higher in mice fed the sorbose diet vs. those fed the control diet. The results suggest that dietary sorbose would benefit patients with diabetes by lowering blood glucose and inhibiting urinary glucose excretion.
在5至11周龄的动物中研究了膳食山梨糖对预防非肥胖糖尿病小鼠糖尿病发病率的影响。当对照饮食中的蔗糖（200 g/kg饮食）被山梨糖替代时，体重显著降低。喂食山梨糖的小鼠血糖水平也降低，但血清胰岛素水平未改变。在实验期间，喂食山梨糖饮食的小鼠尿液中未检测到葡萄糖，但对照组中的一些小鼠尿液中排泄葡萄糖。喂食山梨糖饮食的小鼠心脏、肝脏和左肾的相对重量显著高于喂食对照饮食的小鼠。结果表明，膳食山梨糖可通过降低血糖和抑制尿糖排泄使糖尿病患者受益。
