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右侧脑岛与我们对肢体所属感和对自身行为的自我意识有关。

Right insula for our sense of limb ownership and self-awareness of actions.

机构信息

Section of Neuropsychology, Center of Neurology, Hertie-Institute for Clinical Brain Research, University of Tübingen, Hoppe-Seyler-Str. 3, 72076, Tübingen, Germany.

出版信息

Brain Struct Funct. 2010 Jun;214(5-6):411-7. doi: 10.1007/s00429-010-0250-4. Epub 2010 May 29.

DOI:10.1007/s00429-010-0250-4
PMID:20512380
Abstract

Normally, we are aware that our arms and legs belong to us and not to someone else. However, some stroke patients with hemiparesis/-plegia after right-sided stroke show a disturbed sensation of limb ownership and a disturbed self-awareness of actions and such patients with anosognosia for hemiparesis/plegia typically deny their paresis/-plegia and are convinced that their limbs function normally. They may experience their limb(s) as not belonging to them and may even attribute them to other persons. Modern lesion analyses techniques in such patients and recent neuroimaging results in healthy subjects suggest a prominent role of the right insula for our sense of limb ownership as well as for our feeling of being involved in a movement-our sense of agency. We thus hypothesize that the right insular cortex constitutes a central node of a network involved in human body scheme representation.

摘要

通常,我们清楚地知道自己的胳膊和腿是属于自己的,而不是别人的。然而,一些右侧脑卒中偏瘫患者会表现出肢体所有权感觉障碍和对动作的自我意识障碍,这些失认症患者通常否认偏瘫,并坚信自己的四肢功能正常。他们可能会感觉自己的肢体不属于自己,甚至可能将其归因于其他人。对这些患者的现代病变分析技术和对健康受试者的最新神经影像学结果表明,右侧脑岛在我们的肢体所有权感觉以及我们参与运动的感觉(我们的主体感)中起着重要作用。因此,我们假设右侧脑岛皮质构成了一个涉及人体图式表示的网络的中央节点。

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