Tang Yi-Wei, Stratton Charles W
Department of Pathology and Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.
Clin Lab Med. 2010 Mar;30(1):179-208. doi: 10.1016/j.cll.2010.01.005.
Staphylococcus aureus has been recognized as an important human pathogen for more than 100 years. S aureus has been able to adapt and evolve in terms of its resistance traits and virulence factors; it is among the most important causes of human infections in the twenty-first century. Rapid molecular identification in the clinical microbiology laboratory of these resistance and virulence factors expressed by S aureus will play an important role in the future in decreasing the morbidity and mortality of infections. This article addresses the emerging aspects of infections caused by S aureus, including microbiology, epidemiology, clinical presentation, pathogenesis, diagnosis, treatment and prognosis, and immunity.
100多年来，金黄色葡萄球菌一直被公认为一种重要的人类病原体。金黄色葡萄球菌在耐药性状和毒力因子方面能够适应和进化；它是21世纪人类感染的最重要原因之一。在临床微生物实验室对金黄色葡萄球菌表达的这些耐药和毒力因子进行快速分子鉴定，将在未来降低感染的发病率和死亡率方面发挥重要作用。本文论述了由金黄色葡萄球菌引起的感染的新出现的方面，包括微生物学、流行病学、临床表现、发病机制、诊断、治疗、预后及免疫。
