Department of Neurosurgery, Chuncheon Sacred Heart Hospital, Hallym University, Chuncheon, Korea.
J Korean Med Sci. 2010 Jun;25(6):974-9. doi: 10.3346/jkms.2010.25.6.974. Epub 2010 May 24.
Central retinal artery occlusion (CRAO) causes severe visual loss in affected eye and vision does not recover in more than 90% of the patients. It is believed that it occurs by occlusion of the central retinal artery with small emboli from atherosclerotic plaque of internal cerebral artery. Retina is a part of the brain, thus basically CRAO is corresponding to acute occlusion of intracerebral artery and retinal ischemia is to cerebral stroke. Therefore, intra-arterial thrombolysis (IAT) has been considered as a treatment method in CRAO. Recently, we treated 2 patients diagnosed as CRAO and could achieve complete recanalization on fundus fluorescein angiogram with IAT. Of them, one recovered visual acuity to 20/25. We report our 2 CRAO cases treated with IAT and discuss technical aspects for IAT and management of patient. To the best of our knowledge, this is the first Korean report of IAT for CRAO.
视网膜中央动脉阻塞（CRAO）可导致患眼严重视力丧失，超过 90%的患者视力无法恢复。据信，它是由大脑内部颈内动脉的粥样硬化斑块中的小栓子阻塞中央视网膜动脉引起的。视网膜是大脑的一部分，因此基本上 CRAO 相当于颅内动脉急性阻塞，视网膜缺血相当于脑卒中。因此，已考虑将动脉内溶栓（IAT）作为 CRAO 的一种治疗方法。最近，我们治疗了 2 例诊断为 CRAO 的患者，并通过 IAT 在眼底荧光血管造影上实现了完全再通。其中 1 例视力恢复至 20/25。我们报告了我们通过 IAT 治疗的 2 例 CRAO 病例，并讨论了 IAT 的技术方面和患者管理。据我们所知，这是首例韩国关于 CRAO 的 IAT 报告。
