患有冠状动脉粥样硬化的沙特阿拉伯人的乙酰化表型。
The acetylator phenotypes of Saudi Arabians with coronary arterial atheroma.
作者信息
Evans D A, Wicks J, Higgins J, Assisto M
机构信息
C123 Riyadh Armed Forces Hospital, Riyadh, Kingdom of Saudi Arabia.
出版信息
J Med Genet. 1991 Mar;28(3):192-3. doi: 10.1136/jmg.28.3.192.
The acetylator phenotypes were determined by means of a sulfamethazine test in 101 Saudi Arabian patients with authenticated coronary atheroma; 65 were found to be slow acetylators. This distribution of phenotypes is not significantly different from that in 220 controls, 148 of whom were slow acetylators. This finding makes it unlikely that compounds containing a primary aromatic amino or a hydrazino group are involved in the aetiology or pathogenesis of coronary atheroma.
通过磺胺二甲嘧啶试验对101名经证实患有冠状动脉粥样硬化的沙特阿拉伯患者的乙酰化表型进行了测定；发现65人为慢乙酰化者。这种表型分布与220名对照者的表型分布无显著差异，其中148人为慢乙酰化者。这一发现使得含有伯芳香氨基或肼基的化合物不太可能参与冠状动脉粥样硬化的病因或发病机制。
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