Saafan Ali Mohammad, Salah Manal Mohamed
Dental Laser Applications, Medical Department, The National Institute of Laser Enhanced Sciences (NILES), Cairo University, Egypt.
J Drugs Dermatol. 2010 Apr;9(4):310-4.
To evaluate the efficacy of application of dual long-pulsed dye/Nd:YAG lasers in the management of skin and mucous membrane infantile hemangiomas.
Management of hemangiomas may be a challenge. Different laser systems have been reported to be of significant help for such cases with variable results.
In this study, the authors present a unique sequential laser system, which delivers pulsed dye laser (PDL) 595 nm followed by Nd:YAG 1064 nm, which they have found to be superior and more effective than other reported techniques. Twenty-five cases of infantile hemangiomas in the skin and mucous membrane in the head and neck region were selected to be enrolled in this study. Assessment for progress was achieved clinically.
The authors achieved excellent results in eighteen patients (72%) out of the 25 treated patients, with no recurrence after six-month follow-up. Laser application from skin and mucous membrane sides (sandwich technique) decreased number of sessions.
The sequential application of 595 nm PDL followed by 1064 nm Nd:YAG laser can be considered a superior method for management of infantile hemangiomas, especially in the head and neck region, due to its excellent cosmetic results with fewer treatment sessions.
评估双波长长脉冲染料激光/掺钕钇铝石榴石激光(Nd:YAG激光)联合应用于治疗婴幼儿皮肤及黏膜血管瘤的疗效。
血管瘤的治疗颇具挑战性。据报道,不同的激光系统对此类病例有显著帮助,但效果各异。
在本研究中,作者介绍了一种独特的序贯激光系统,该系统先发射595nm脉冲染料激光(PDL),随后发射1064nm Nd:YAG激光,他们发现此系统比其他已报道的技术更优越、更有效。本研究选取了25例头颈部皮肤及黏膜婴幼儿血管瘤患者。通过临床评估病情进展。
在25例接受治疗的患者中,18例(72%)取得了优异的治疗效果,随访6个月无复发。从皮肤和黏膜两侧进行激光治疗(三明治技术)减少了治疗次数。
595nm PDL序贯1064nm Nd:YAG激光的联合应用可被视为治疗婴幼儿血管瘤的一种优越方法,尤其是对头颈部血管瘤,因其能获得优异的美容效果且治疗次数较少。