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多发性颅内动脉瘤合并结节性硬化症:因动眼神经麻痹而在成年期被诊断为不典型结节性硬化症。

Tuberous sclerosis with multiple intracranial aneurysms: atypical tuberous sclerosis diagnosed in adult due to third nerve palsy.

机构信息

University of Alabama at Birmingham, Birmingham, Alabama, USA.

出版信息

Acta Neurol Belg. 2010 Mar;110(1):89-92.

Abstract

Association between tuberous sclerosis and intracranial aneurysms is not well established and is at best suspicious. Sporadic cases of incidentally detected unruptured single, anterior circulation aneurysms have been reported in the literature in cases of typical tuberous sclerosis. We herein describe an unrecognised case of atypical tuberous sclerosis with bilateral PCom aneurysms which was diagnosed retrospectively while evaluating an unexplained intracranial hemorrhage with third nerve palsy. We intend this case would again strengthen a possible association between TS and intracranial aneurysms and lead to a systematic larger prospective/retrospective analysis.

摘要

结节性硬化症与颅内动脉瘤之间的关联尚未得到充分证实,最多只是可疑。在典型结节性硬化症的病例中,文献中曾报道过偶发的未破裂单发、前循环动脉瘤。我们在此描述了一例不典型结节性硬化症伴双侧 PCom 动脉瘤的病例,该病例是在评估不明原因的伴有动眼神经麻痹的颅内出血时回顾性诊断出来的。我们希望这个病例能再次证实 TS 与颅内动脉瘤之间的可能关联,并促使进行系统的更大规模的前瞻性/回顾性分析。

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