Aissi M, Younes-Mhenni S, Jerbi-Ommezzine S, Boughammoura-Bouatay A, Frih-Ayed M, Sfar M H
Service de neurologie, CHU de Monastir, avenue 1(er) juin, Monastir 5000, Tunisia.
Rev Neurol (Paris). 2010 Nov;166(11):935-9. doi: 10.1016/j.neurol.2009.12.011. Epub 2010 May 15.
Tuberous sclerosis is an autosomal dominant inherited phakomatosis. It is associated with a wide variety of central nervous system abnormalities, but intracranial aneurysms are rare.
We report a 34-year-old patient fulfilling the diagnostic criteria of tuberous sclerosis in association with intracranial aneurysm.
This association has been reported in only 17 other cases of tuberous sclerosis. We discuss the etiopathogenic mechanisms, preferential localizations and the various therapeutic propositions.