p38MAPK 在应激早期转录反应中的核心作用。
A central role for p38 MAPK in the early transcriptional response to stress.
机构信息
Faculty of Life Sciences, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, UK.
出版信息
BMC Biol. 2010 Apr 27;8:47. doi: 10.1186/1741-7007-8-47.
Abstract
The mitogen-activated protein kinase p38 (p38 MAPK) is activated by a number of stresses. A recent study in BMC Genomics has uncovered the early transcriptional responses to three types of stress and has demonstrated a central role for p38 MAPK in mediating these responses. See research article http://www.biomedcentral.com/1471-2164/11/144.
摘要
丝裂原活化蛋白激酶 p38（p38 MAPK）可被多种应激激活。最近在 BMC 基因组学上的一项研究揭示了对三种应激的早期转录反应，并证实 p38 MAPK 在介导这些反应中起核心作用。参见研究文章 http://www.biomedcentral.com/1471-2164/11/144。
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