National Cancer Institute of Mexico (INCan), Mexico City, Mexico.
Pathobiology. 2010;77(3):147-54. doi: 10.1159/000292648. Epub 2010 May 28.
A tumor bank (TB) is an ordered collection of neoplastic samples, normal tissue, and/or fluids preserved under optimal conditions, as well as storing patients' clinical information. The objective of this article is to outline the planning and logistics necessary for the functioning of the Instituto Nacional de Cancerología (INCan) TB in Mexico City. For the planning and logistics of a TB, several technical, legal, medical, structural, and physical aspects were considered, which can be grouped under four headings: (1) design and structure, (2) equipping the area and informatics, (3) ethical-legal aspects, and (4) sample collection, preservation, and quality control. One crucial element of interinstitutional interest will be the transfer of these concepts to the different oncological centers, integrating in this manner a network that enables the exploration of the different pathologies from therapeutic, epidemiological, and molecular points of view.
肿瘤库(tumor bank,TB)是一种有序收集的肿瘤样本、正常组织和/或液体的集合,保存在最佳条件下,并存储患者的临床信息。本文的目的是概述墨西哥城国立癌症研究所(INCan)TB 的功能所需的规划和物流。对于 TB 的规划和物流,考虑了几个技术、法律、医学、结构和物理方面的因素,可以分为以下四个标题:(1)设计和结构,(2)设备区域和信息学,(3)伦理法律方面,以及(4)样本收集、保存和质量控制。机构间感兴趣的一个关键因素将是将这些概念转移到不同的肿瘤中心,从而整合一个网络,从治疗、流行病学和分子的角度探索不同的病理。