Skipenko O G, Ponomar' S A, Bedzhanian A L, Sekacheva M I, Abdullaev A G
Khirurgiia (Mosk). 2010(3):4-10.
Retrospective analysis of treatment results was carried out in 37 patients that had been treated during 1984-2009 years. Mean age of the patients was 50.7 years; among them 94.6% were women. 8 (21.6%) patients had serous cystadenoma, 21 (56.8%) patients - mucinous cystadenoma, 7 (18,9%) patients - cystadenocarcinoma and 1 (2.7%) patient - intraductal papillary-mucinous tumor. Distal pancreatic resection was carried out to 19 patients, pancreatoduodenal resection - in 5 patients, enucleation - in 10 patients, midline resection - in 1 patient, pancreatectomy - in 2 patients. The frequency of complications amounted 35.1%; lethal outcomes were not observed. Pancreatitis (in 7 patients) and pancreatic fistula (in 4 patients) were the most common complications. Re-laparotomy was necessary for destructive pancreatitis in 2 observations. Other complications were treated conservatively. Long-term results were studied in 28 (76%) patients. Mean duration of the observation was 87,3 months (6-120 months). 5-year survival rate amounted 100% among patients with benign cystic tumors of the pancreas and 25% in patients with cystadenocarcinoma. It is drawn a conclusion that complete recovery is quite possible in patients with benign tumors whereas treatment of the patients with invasive cystadenocarcinoma demonstrate poor results in long-term period.
对1984年至2009年期间接受治疗的37例患者的治疗结果进行了回顾性分析。患者的平均年龄为50.7岁;其中94.6%为女性。8例(21.6%)患者患有浆液性囊腺瘤,21例(56.8%)患者患有黏液性囊腺瘤,7例(18.9%)患者患有囊腺癌,1例(2.7%)患者患有导管内乳头状黏液性肿瘤。19例患者进行了胰体尾切除术,5例患者进行了胰十二指肠切除术,10例患者进行了肿瘤摘除术,1例患者进行了中线切除术,2例患者进行了全胰切除术。并发症发生率为35.1%;未观察到死亡病例。胰腺炎(7例患者)和胰瘘(4例患者)是最常见的并发症。2例患者因坏死性胰腺炎需要再次开腹手术。其他并发症采用保守治疗。对28例(76%)患者进行了长期随访。平均随访时间为87.3个月(6 - 120个月)。胰腺良性囊性肿瘤患者的5年生存率为100%,囊腺癌患者的5年生存率为25%。得出的结论是,良性肿瘤患者完全康复的可能性很大,而浸润性囊腺癌患者的长期治疗效果较差。