1型糖尿病患者关节活动度的局限性
[Limitations of joint mobility in patients with type 1 diabetes mellitus].
作者信息
Rozadilla A, Montaña E, Nolla J M, Soler J, Roig Escofet D
机构信息
Servicio de Reumatología, Hospital de Bellvitge-Princeps d'Espanya, L'Hospitalet de Llobregat, Barcelona.
出版信息
Med Clin (Barc). 1991 Apr 13;96(14):530-3.
BACKGROUND
To assess limitation of joint mobility in patients with type I diabetes mellitus and to evaluate its relation with retinopathy, joint mobility was prospectively assessed in 96 diabetic patients and 68 healthy controls.
METHODS
Joint mobility was explored with the praying maneuver and the measurement in mobility degrees of the third and fifth metacarpophalangeal joints, wrists and elbows. The degree of metabolic control was assessed with the mean glycosylated hemoglobin in the last two years. Retinopathy was investigated with direct funduscopy. The results were statistically evaluated with chi-square and Student's t tests and the linear coefficient.
RESULTS
A reduced joint mobility was found in 41 diabetics and 5 controls (p less than 0.0001). The reduction in joint mobility was related with the patients' age but not with the degree of metabolic control. 85% of diabetics with joint involvement had retinopathy of some degree.
CONCLUSIONS
A limited joint mobility is a common complication of type I diabetes mellitus. The demonstration of this abnormality in diabetic patients might represent a first and simple marker of microangiopathy.
背景
为评估1型糖尿病患者关节活动度的受限情况，并评估其与视网膜病变的关系，我们对96例糖尿病患者和68例健康对照者进行了关节活动度的前瞻性评估。
方法
采用祈祷动作以及测量第三和第五掌指关节、腕关节和肘关节的活动度来探究关节活动度。通过过去两年的平均糖化血红蛋白评估代谢控制程度。采用直接检眼镜检查视网膜病变。结果采用卡方检验、学生t检验和线性系数进行统计学评估。
结果
41例糖尿病患者和5例对照者存在关节活动度降低（p<0.0001）。关节活动度降低与患者年龄有关，而与代谢控制程度无关。85%有关节受累的糖尿病患者有某种程度的视网膜病变。
结论
关节活动度受限是1型糖尿病的常见并发症。在糖尿病患者中证实这种异常可能是微血管病变的首个简单标志物。
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