Campbell R R, Hawkins S J, Maddison P J, Reckless J P
Ann Rheum Dis. 1985 Feb;44(2):93-7. doi: 10.1136/ard.44.2.93.
The relationship of limited joint mobility and finger joint contractures in diabetics to age of onset, duration, and control of diabetes has not been established. We measured the mobility of metacarpophalangeal, wrist, elbow, and ankle joints and assessed the prevalence of finger joint contractures in 254 young diabetics and 110 controls. The presence of microvascular disease was assessed by ophthalmoscopy and urine analysis for proteinuria. An estimate of long-term diabetic control was obtained from a postal questionnaire. A generalised reduction in joint mobility was present in diabetics of all ages two years after diagnosis. The reduction in joint mobility in controls between the ages of 12 and 13 was exaggerated in the diabetics. Diabetics diagnosed before puberty were more severely affected than those with a postpubertal onset, independent of duration of diabetes. Finger joint contractures were a significant feature of longstanding diabetics (nine years or more duration) only.
糖尿病患者中有限的关节活动度和手指关节挛缩与发病年龄、病程及糖尿病控制情况之间的关系尚未明确。我们测量了254例年轻糖尿病患者和110例对照者的掌指关节、腕关节、肘关节和踝关节的活动度,并评估了手指关节挛缩的患病率。通过眼底镜检查和尿蛋白分析评估微血管疾病的存在情况。通过邮寄问卷获得长期糖尿病控制情况的估计值。诊断后两年,各年龄段的糖尿病患者均存在关节活动度普遍降低的情况。12至13岁对照组的关节活动度降低在糖尿病患者中更为明显。青春期前诊断的糖尿病患者比青春期后发病的患者受影响更严重,且与糖尿病病程无关。手指关节挛缩仅是病程较长(九年或更长时间)的糖尿病患者的一个显著特征。