Lukás Karel, Parízek Antonín, Kotlas Jaroslav, Novotný Ales
Univerzita Karlova v Praze, 1. lékarská fakulta, IV. interní klinika VFN, Praha.
Cas Lek Cesk. 2010;149(4):163-4, 166-72.
Inflammatory bowel disease (IBD) commonly affects women during the reproductive years. Opinion on the effect of IBD on fertility, conception, pregnancy and breastfeeding is varied. IBD does not have probably adverse effect on the outcome of pregnancy. Pregnancy in IBD patients should be closely monitored. This review provides the most current information on the inheritance, fertility, pregnancy, outcomes, foetal development and management of disease during pregnancy, and safety of medications in pregnancy and breastfeeding.
炎症性肠病(IBD)在育龄期女性中较为常见。关于IBD对生育力、受孕、妊娠及母乳喂养影响的观点不一。IBD可能不会对妊娠结局产生不利影响。IBD患者妊娠时应密切监测。本综述提供了有关IBD的遗传、生育力、妊娠、结局、胎儿发育、孕期疾病管理以及孕期和母乳喂养期间药物安全性的最新信息。