Aly Mohamed Y F, Tsutsumi Kosuke, Nakamura Masafumi, Sato Norihiro, Takahata Shunichi, Ueda Junji, Shimizu Shuji, Redwan Alaa A, Tanaka Masao
Department of Endoscopic Diagnostics and Therapeutics, Kyushu University Hospital, Fukuoka, Japan.
J Laparoendosc Adv Surg Tech A. 2010 Jun;20(5):435-40. doi: 10.1089/lap.2009.0412.
Laparoscopic distal pancreatectomy (LDP) has been shown to be an effective surgical option for benign lesions in the body and tail of the pancreas. However, its advantages and disadvantages have not been well characterized. In this study, we compared the outcomes of LDP and open pancreatectomy performed in our clinic.
Peri- and postoperative outcomes were retrospectively compared between patients with benign pancreatic disorders who underwent open distal pancreatectomy (ODP) (n = 35) and those who underwent LDP (n = 40). The peri- and postoperative factors analyzed included operative time, blood loss, hospital stay, postoperative recovery, biochemical findings, and complications.
LDP was associated with significantly less operative blood loss (363 versus 606 mL; P = 0.001) and shorter hospital stay (22 versus 27 day; P = 0.009), but longer operative time (342 versus 250 min; P = 0.000), compared with ODP. There were no significant differences between the two groups in complication rates or postoperative recovery, except for the significantly shorter duration of postoperative pain-killer intake and earlier improvement of the biochemical analysis in LDP than in ODP.
LDP appears to be a safe, desirable procedure for the management of benign pancreatic diseases, with outcomes similar to ODP.
腹腔镜胰体尾切除术（LDP）已被证明是治疗胰腺体尾部良性病变的一种有效手术方式。然而，其优缺点尚未得到充分描述。在本研究中，我们比较了在我们诊所进行的LDP和开放胰腺切除术的结果。
对接受开放远端胰腺切除术（ODP）（n = 35）和LDP（n = 40）的良性胰腺疾病患者的围手术期和术后结果进行回顾性比较。分析的围手术期和术后因素包括手术时间、失血量、住院时间、术后恢复情况、生化检查结果和并发症。
与ODP相比，LDP的术中失血量显著减少（363 vs 606 mL；P = 0.001），住院时间缩短（22 vs 27天；P = 0.009），但手术时间更长（342 vs 250分钟；P = 0.000）。两组在并发症发生率或术后恢复方面无显著差异，但LDP的术后止痛药服用时间明显短于ODP，生化分析改善更早。
LDP似乎是治疗良性胰腺疾病的一种安全、理想的手术方式，其结果与ODP相似。
