• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新型甲型 H1N1 流感严重并发症的危险因素:意大利住院患者分析。

Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy.

机构信息

Infectious Diseases Division, San Martino Hospital and University of Genoa School of Medicine, Genoa, Italy.

出版信息

Clin Microbiol Infect. 2011 Feb;17(2):247-50. doi: 10.1111/j.1469-0691.2010.03275.x.

DOI:10.1111/j.1469-0691.2010.03275.x
PMID:20518797
Abstract

Eighty-one patients affected by the novel influenza A (H1N1), hospitalized in North-western Italy, were studied. The median age was 32 years (range 1-81 years). Fifty-six (69%) had an underlying medical condition, including lung disorders (asthma or chronic obstructive pulmonary disease) in 34% and obesity in 25%. Fifty percent of them had pneumonia, 12% were admitted to the intensive care unit and 3% died. Antiviral treatment was initiated in 75% of patients started within 48 h. Older age and lung and neurocognitive disorders were associated with severe disease and death.

摘要

研究了 81 名在意大利西北部住院的新型甲型 H1N1 流感患者。中位年龄为 32 岁(范围 1-81 岁)。56 名(69%)有基础疾病,包括肺部疾病(哮喘或慢性阻塞性肺疾病)占 34%和肥胖占 25%。50%的患者患有肺炎,12%的患者住进重症监护病房,3%的患者死亡。75%的患者在发病后 48 小时内开始接受抗病毒治疗。年龄较大、肺部和神经认知障碍与严重疾病和死亡相关。

相似文献

1
Risk factors for severe complications of the novel influenza A (H1N1): analysis of patients hospitalized in Italy.新型甲型 H1N1 流感严重并发症的危险因素:意大利住院患者分析。
Clin Microbiol Infect. 2011 Feb;17(2):247-50. doi: 10.1111/j.1469-0691.2010.03275.x.
2
Fatalities associated with the 2009 H1N1 influenza A virus in New York city.与 2009 年纽约市甲型 H1N1 流感病毒相关的死亡病例。
Clin Infect Dis. 2010 Jun 1;50(11):1498-504. doi: 10.1086/652446.
3
Hospitalized patients with 2009 pandemic influenza A (H1N1) virus infection in the United States--September-October 2009.美国 2009 年大流行性流感 A(H1N1)病毒感染住院患者-2009 年 9 月至 10 月。
Clin Infect Dis. 2011 Jan 1;52 Suppl 1:S50-9. doi: 10.1093/cid/ciq021.
4
Adult intensive-care patients with 2009 pandemic influenza A(H1N1) infection.成人重症监护病房 2009 年大流行性流感 A(H1N1)感染患者。
Epidemiol Infect. 2011 Aug;139(8):1202-9. doi: 10.1017/S0950268810002414. Epub 2010 Oct 26.
5
Influenza-associated pneumonia among hospitalized patients with 2009 pandemic influenza A (H1N1) virus--United States, 2009.2009 年甲型 H1N1 流感大流行期间住院患者的流感相关性肺炎——美国,2009 年。
Clin Infect Dis. 2012 May;54(9):1221-9. doi: 10.1093/cid/cis197. Epub 2012 Mar 20.
6
Prospective evaluation of epidemiological, clinical, and microbiological features of pandemic influenza A (H1N1) virus infection in Italy.意大利甲型 H1N1 流感大流行病毒感染的前瞻性评估:流行病学、临床和微生物学特征。
J Med Virol. 2011 Dec;83(12):2057-65. doi: 10.1002/jmv.22231.
7
High mortality from respiratory failure secondary to swine-origin influenza A (H1N1) in South Africa.南非因猪源甲型 H1N1 流感导致呼吸衰竭死亡率高。
QJM. 2010 May;103(5):319-25. doi: 10.1093/qjmed/hcq022. Epub 2010 Mar 10.
8
Pneumonia risk factors and clinical features of hospitalized patients older than 15 years with pandemic influenza A (H1N1) in South Korea: a multicenter study.韩国 15 岁以上住院甲型 H1N1 流感患者的肺炎危险因素和临床特征:一项多中心研究。
Diagn Microbiol Infect Dis. 2011 Jun;70(2):230-5. doi: 10.1016/j.diagmicrobio.2011.01.005.
9
Impact of the novel influenza A (H1N1) during the 2009 autumn-winter season in a large hospital setting in Santiago, Chile.2009 年智利圣地亚哥一家大型医院秋冬季新型甲型流感(H1N1)的影响。
Clin Infect Dis. 2010 Mar 15;50(6):860-8. doi: 10.1086/650750.
10
Hospitalized patients with novel influenza A (H1N1) virus infection - California, April-May, 2009.2009年4月至5月加利福尼亚州甲型H1N1流感病毒感染住院患者
MMWR Morb Mortal Wkly Rep. 2009 May 22;58(19):536-41.

引用本文的文献

1
Pre-Existing Allergic Inflammation Alters Both Innate and Adaptive Immune Responses in Mice Co-Infected with Influenza Virus.既往存在的变应性炎症改变了感染流感病毒的小鼠的固有免疫和适应性免疫反应。
Int J Mol Sci. 2025 Apr 8;26(8):3483. doi: 10.3390/ijms26083483.
2
Measuring the disease burden of seasonal influenza in Germany 2015 - 2020 using the incidence-based disability-adjusted life years (DALYs).利用基于发病率的伤残调整生命年(DALYs)衡量2015 - 2020年德国季节性流感的疾病负担。
BMC Infect Dis. 2025 Mar 26;25(1):413. doi: 10.1186/s12879-025-10613-2.
3
Mortality Risk Among Patients With Influenza Illness Admitted to the ICU: A Systematic Review and Meta-Analysis.
入住重症监护病房的流感患者的死亡风险:一项系统评价和荟萃分析
Influenza Other Respir Viruses. 2025 Mar;19(3):e70073. doi: 10.1111/irv.70073.
4
Obesity exacerbates influenza-induced respiratory disease via the arachidonic acid-p38 MAPK pathway.肥胖通过花生四烯酸-p38丝裂原活化蛋白激酶途径加重流感诱导的呼吸道疾病。
Front Pharmacol. 2023 Aug 23;14:1248873. doi: 10.3389/fphar.2023.1248873. eCollection 2023.
5
Adenovirus transduction to express human ACE2 causes obesity-specific morbidity in mice, impeding studies on the effect of host nutritional status on SARS-CoV-2 pathogenesis.腺病毒转导表达人血管紧张素转换酶 2 会导致肥胖特异性发病,从而阻碍宿主营养状态对 SARS-CoV-2 发病机制影响的研究。
Virology. 2021 Nov;563:98-106. doi: 10.1016/j.virol.2021.08.014. Epub 2021 Sep 3.
6
Obesity, a major risk factor for immunity and severe outcomes of COVID-19.肥胖是 COVID-19 免疫和严重后果的一个主要危险因素。
Biosci Rep. 2021 Aug 27;41(8). doi: 10.1042/BSR20210979.
7
Comorbidity Networks in Cardiovascular Diseases.心血管疾病中的共病网络
Front Physiol. 2020 Aug 28;11:1009. doi: 10.3389/fphys.2020.01009. eCollection 2020.
8
COVID-19: what have we learned?新冠病毒肺炎:我们学到了什么?
J Bras Pneumol. 2020 Jun 15;46(3):e20200216. doi: 10.36416/1806-3756/e20200216.
9
Impact of Obesity on Influenza A Virus Pathogenesis, Immune Response, and Evolution.肥胖对甲型流感病毒发病机制、免疫反应和进化的影响。
Front Immunol. 2019 May 10;10:1071. doi: 10.3389/fimmu.2019.01071. eCollection 2019.
10
Hospitalization Fatality Risk of Influenza A(H1N1)pdm09: A Systematic Review and Meta-Analysis.甲型H1N1流感大流行病毒的住院病死率:一项系统评价与荟萃分析
Am J Epidemiol. 2015 Aug 15;182(4):294-301. doi: 10.1093/aje/kwv054. Epub 2015 Jul 18.