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Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients.在丹麦囊性纤维化诊所中，洋葱伯克霍尔德菌复合种的分布不同寻常，这可能是由于患者之间的传播受到限制。
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Genomics of an endemic cystic fibrosis Burkholderia multivorans strain reveals low within-patient evolution but high between-patient diversity.地方性囊性纤维化伯克霍尔德菌的基因组研究揭示了其在患者体内的低进化速度，但在患者间具有高度多样性。
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Taxon K, a complex within the Burkholderia cepacia complex, comprises at least two novel species, Burkholderia contaminans sp. nov. and Burkholderia lata sp. nov.分类单元K是洋葱伯克霍尔德菌复合群中的一个复合体，包含至少两个新物种，即污染伯克霍尔德菌新种和宽伯克霍尔德菌新种。
Int J Syst Evol Microbiol. 2009 Jan;59(Pt 1):102-11. doi: 10.1099/ijs.0.001123-0.
2
Burkholderia cepacia complex epidemiology in persons with cystic fibrosis from Australia and New Zealand.澳大利亚和新西兰囊性纤维化患者中洋葱伯克霍尔德菌复合体的流行病学研究
Res Microbiol. 2008 Apr;159(3):194-9. doi: 10.1016/j.resmic.2008.01.001. Epub 2008 Feb 2.
3
Comparative phylogenies of Burkholderia, Ralstonia, Comamonas, Brevundimonas and related organisms derived from rpoB, gyrB and rrs gene sequences.基于rpoB、gyrB和rrs基因序列的伯克霍尔德菌属、罗尔斯通氏菌属、丛毛单胞菌属、短波单胞菌属及相关微生物的比较系统发育研究
Res Microbiol. 2008 Apr;159(3):169-77. doi: 10.1016/j.resmic.2007.12.005. Epub 2007 Dec 24.
4
The changing epidemiology of Burkholderia species infection at an adult cystic fibrosis centre.一家成人囊性纤维化中心伯克霍尔德菌属感染的流行病学变化
J Cyst Fibros. 2008 Sep;7(5):368-72. doi: 10.1016/j.jcf.2008.01.002. Epub 2008 Feb 13.
5
Development of a species-specific fur gene-based method for identification of the Burkholderia cepacia complex.开发一种基于物种特异性皮毛基因的方法用于鉴定洋葱伯克霍尔德菌复合体。
J Clin Microbiol. 2008 Feb;46(2):447-55. doi: 10.1128/JCM.01460-07. Epub 2007 Dec 5.
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Environmental Burkholderia cepacia complex isolates in human infections.人类感染中环境来源的洋葱伯克霍尔德菌复合体分离株
Emerg Infect Dis. 2007 Mar;13(3):458-61. doi: 10.3201/eid1303.060403.
7
Exceptionally high representation of Burkholderia cepacia among B. cepacia complex isolates recovered from the major Portuguese cystic fibrosis center.在从葡萄牙主要囊性纤维化中心分离出的洋葱伯克霍尔德菌复合体菌株中，洋葱伯克霍尔德菌的占比极高。
J Clin Microbiol. 2007 May;45(5):1628-33. doi: 10.1128/JCM.00234-07. Epub 2007 Mar 14.
8
Simultaneous coinfection by multiple strains during Burkholderia cepacia complex infection in cystic fibrosis.在囊性纤维化患者的洋葱伯克霍尔德菌复合体感染期间，多种菌株同时发生合并感染。
Diagn Microbiol Infect Dis. 2006 Feb;54(2):95-8. doi: 10.1016/j.diagmicrobio.2005.08.020. Epub 2006 Jan 9.
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Transmission of Burkholderia cepacia complex: evidence for new epidemic clones infecting cystic fibrosis patients in Italy.洋葱伯克霍尔德菌复合体的传播：意大利感染囊性纤维化患者的新流行克隆的证据。
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10
Multilocus sequence typing scheme that provides both species and strain differentiation for the Burkholderia cepacia complex.多位点序列分型方案可对洋葱伯克霍尔德菌复合体进行菌种和菌株鉴别。
J Clin Microbiol. 2005 Sep;43(9):4665-73. doi: 10.1128/JCM.43.9.4665-4673.2005.

在丹麦囊性纤维化诊所中，洋葱伯克霍尔德菌复合种的分布不同寻常，这可能是由于患者之间的传播受到限制。

Unusual distribution of Burkholderia cepacia complex species in Danish cystic fibrosis clinics may stem from restricted transmission between patients.

机构信息

Department of Clinical Microbiology, Aarhus University Hospital, Skejby, DK-8200 Aarhus N, Denmark.

出版信息

J Clin Microbiol. 2010 Aug;48(8):2981-3. doi: 10.1128/JCM.00383-10. Epub 2010 Jun 2.

DOI:10.1128/JCM.00383-10
PMID:20519474
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2916570/
Abstract

Forty-four of 48 Burkholderia cepacia complex strains cultured from Danish cystic fibrosis patients were Burkholderia multivorans, a distribution of species that has not been reported before. Although cases of cross infections were demonstrated, no major epidemic clone was found. The species distribution may represent the sporadic acquisition of bacteria from the environment.

摘要

从丹麦囊性纤维化患者中培养的 48 株洋葱伯克霍尔德菌复合体菌株中，有 44 株为洋葱伯克霍尔德菌，这种物种分布以前从未报道过。尽管已经证明存在交叉感染的情况，但没有发现主要的流行克隆。这种物种分布可能代表了从环境中偶然获得细菌的情况。