Asgeirsson Hilmar, Sigurdardottir Bryndis
Laeknabladid. 2010 Jun;96(6):423-5. doi: 10.17992/lbl.2010.06.302.
Nocardia is a rare pathogen of mainly immunocomprised patients. Only two cases of nocardiosis have previously been identified in Iceland.
A 92-year-old male on glucocorticoid therapy with metastatic bladder cancer presented with two weeks history of progressive swelling and erythema of the hand and deteriorating cognitive functioning. A brain lesion and pulmonary nodules were identified and Nocardia farcinia was cultured from a hand abscess. The patient was initially treated with trimethoprim/sulfamethoxazole but because of rapid deterioration and old age an end-of-life decision was made.
This case of nocardiosis illustrates the importance of uncommon opportunistic infections in immunocompromised Icelandic patients.
诺卡菌是主要感染免疫功能低下患者的一种罕见病原体。此前在冰岛仅确诊过两例诺卡菌病病例。
一名92岁男性,因转移性膀胱癌正在接受糖皮质激素治疗,出现手部进行性肿胀和红斑两周,认知功能逐渐恶化。发现脑部有病变及肺部有结节,从手部脓肿中培养出豚鼠耳炎诺卡菌。患者最初接受甲氧苄啶/磺胺甲恶唑治疗,但由于病情迅速恶化及年事已高,做出了临终决定。
该例诺卡菌病病例说明了免疫功能低下的冰岛患者发生罕见机会性感染的重要性。