Alm Hannelore, Kuhlmann Simone, Langhammer Martina, Tuchscherer Armin, Torner Helmut, Reinsch Norbert
Research Unit Reproductive Biology, FBN Research Institute for the Biology of Farm Animals, Dummerstorf, Germany.
J Reprod Dev. 2010 Aug;56(4):449-53. doi: 10.1262/jrd.09-224h. Epub 2010 Jun 1.
The aim of this study was to evaluate the prevalence of follicles with more than one oocyte (polyovular follicles, POFs) in mouse lines selected for high fecundity. The ovaries of 18 mice, 6 each from 3 different lines, were examined to evaluate the number of POFs and the follicular histology. Polyovular follicles were observed in the two high fecundity breeds, FL1 and FL2, as well as in the unselected control line, DUKsi. The highest number of POFs per ovary (27.0 +/- 7.2) was found in the FL1 line. The FL2 and DUKsi lines had 1.9 +/- 0.7 and 0.6 +/- 0.3 polyovular follicles per ovary, respectively. Most of the POFs contained 2 oocytes (>80%), but occasionally follicles containing up to 7 oocytes were observed. Follicles with more than 2 oocytes were observed in the FL1 line only.
本研究的目的是评估为高繁殖力选育的小鼠品系中存在多个卵母细胞的卵泡（多卵卵泡，POF）的发生率。对18只小鼠的卵巢进行了检查，这18只小鼠来自3个不同品系，每个品系6只，以评估多卵卵泡的数量和卵泡组织学。在两个高繁殖力品系FL1和FL2以及未选择的对照品系DUKsi中均观察到了多卵卵泡。FL1品系每个卵巢中多卵卵泡的数量最多（27.0±7.2）。FL2和DUKsi品系每个卵巢分别有1.9±0.7和0.6±0.3个多卵卵泡。大多数多卵卵泡含有2个卵母细胞（>80%），但偶尔也观察到含有多达7个卵母细胞的卵泡。仅在FL1品系中观察到含有超过2个卵母细胞的卵泡。
