Ripoli Juliana, Miszputen Sender Jankiel, Ambrogini Orlando, Carvalho Luciana de
Departamento de Gastroenterologia Clínica, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Arq Gastroenterol. 2010 Jan-Mar;47(1):49-55. doi: 10.1590/s0004-28032010000100009.
Ulcerative colitis is an inflammatory bowel disease involving superficial inflammation of the mucosa of the colon, rectum, and anus, sometimes including the terminal ileum. When in clinical activity, the disease is characterized by various daily evacuations containing blood, mucus and/or pus alternating periods of remission.
To compare nutritional parameters (dietary, biochemical and anthropometric) among patients with ulcerative colitis followed up on an outpatient basis over a period of 1 year and during periods of intestinal inflammatory activity and remission.
Sixty-five patients were studied over a period of 1 year and divided into two groups: group 1 with inflammatory disease activity (n = 24), and group 2 without disease activity (n = 41). Anthropometric measures, biochemical parameters, quantitative food intake, and qualitative food frequency were analyzed.
A significant reduction in body mass index and weight and in the intake of energy, proteins, lipids, calcium, iron and phosphorus was observed in the group with inflammatory activity (group 1) when compared to the period of clinical remission. The most affected food groups were cereals, legumes, oils, and fats. In contrast, in group 2 significant differences in triceps and sub scapular skin fold thickness, total protein, hemoglobin and hematocrit were observed between the first and final visit. Calcium and vitamin B6 intake, as well as the consumption of legumes, meat and eggs, and sugar and sweets, was significantly higher than on the first visit.
Patients with ulcerative colitis followed up on an outpatient basis tend to be well nourished. However, the nutritional aspects studied tend to worsen during the period of inflammatory disease activity.
溃疡性结肠炎是一种炎症性肠病，累及结肠、直肠和肛门黏膜的表层炎症，有时包括回肠末端。在临床活动期，该病的特征是每日排出含有血液、黏液和/或脓液的粪便，且与缓解期交替出现。
比较溃疡性结肠炎患者在门诊随访1年期间以及肠道炎症活动期和缓解期的营养参数（饮食、生化和人体测量学参数）。
对65例患者进行了为期1年的研究，并将其分为两组：第1组为炎症性疾病活动期患者（n = 24），第2组为无疾病活动期患者（n = 41）。分析了人体测量指标、生化参数、食物摄入量和食物频率。
与临床缓解期相比，炎症活动期组（第1组）的体重指数、体重以及能量、蛋白质、脂质、钙、铁和磷的摄入量显著降低。受影响最大的食物类别是谷物、豆类、油类和脂肪类。相比之下，第2组在首次就诊和最后就诊之间，肱三头肌和肩胛下皮褶厚度、总蛋白、血红蛋白和血细胞比容存在显著差异。钙和维生素B6的摄入量，以及豆类、肉类和蛋类、糖和甜食的消费量均显著高于首次就诊时。
门诊随访的溃疡性结肠炎患者营养状况往往良好。然而，所研究的营养方面在炎症性疾病活动期往往会恶化。
