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可吸收性磷酸三钙骨水泥增强缝线锚钉固定强度。

Bioabsorbable tricalcium phosphate bone cement strengthens fixation of suture anchors.

机构信息

VA Bone and Joint Rehabilitation Research and Development Center, Palo Alto, CA, USA.

出版信息

Clin Orthop Relat Res. 2010 Dec;468(12):3406-12. doi: 10.1007/s11999-010-1412-7. Epub 2010 Jun 3.

Abstract

BACKGROUND

Failure of suture anchor fixation in rotator cuff repair can occur at different interfaces. Prior studies show fixation at the bone-anchor interface can be augmented using polymethylmethacrylate (PMMA) cement, and screw fixation into bone can be strengthened using bioabsorbable tricalcium phosphate cement.

QUESTIONS/PURPOSES: We wished to determine whether augmentation of suture anchor fixation using bioabsorbable tricalcium phosphate cement would increase pullout strength of suture anchors from bone and the number of cycles to failure, to determine the mode of failure after cement augmentation, and to compare strength and mode of failure with those after augmentation with PMMA.

METHODS

We used 10 matched pairs of cadaveric proximal humeri and implanted a metal screw-type suture anchor in one side and on the other side injected tricalcium phosphate cement into the anchor holes before anchor placement. We tested all specimens to failure using a ramped cyclic loading protocol.

RESULTS

Tricalcium phosphate cement augmentation increased the final load to failure by 29% and the number of cycles to failure by 20%. Visual inspection confirmed that failure occurred at the cement-bone interface.

CONCLUSIONS

Tricalcium phosphate cement appears to augment suture anchor fixation into bone, reducing the risk of anchor pullout and failure.

CLINICAL RELEVANCE

When relying on suture anchor fixation in bone of questionable quality, we suggest considering augmentation of suture anchor fixation with bioabsorbable cement. This method also provides potential for bioabsorbability and may be more amenable to arthroscopic application.

摘要

背景

肩袖修复中缝线锚钉固定失败可发生于不同界面。既往研究显示,可通过聚甲基丙烯酸甲酯(PMMA)胶增强骨-锚钉界面的固定,也可通过生物可吸收磷酸三钙(TCP)胶增强螺钉在骨内的固定。

问题/目的:我们希望确定生物可吸收 TCP 胶增强缝线锚钉固定是否能增加缝线锚钉从骨内拔出的强度和失效循环次数,确定增强后锚钉的失效模式,并与 PMMA 增强后的强度和失效模式进行比较。

方法

我们使用 10 对匹配的尸体肱骨近端,在一侧植入金属螺钉型缝线锚钉,另一侧在放置锚钉前将 TCP 胶注入锚钉孔内。我们使用斜坡循环加载方案对所有标本进行失效测试。

结果

TCP 胶增强使最终失效负荷增加了 29%,失效循环次数增加了 20%。肉眼检查证实失效发生在水泥-骨界面。

结论

TCP 胶似乎增强了缝线锚钉在骨内的固定,降低了锚钉拔出和失效的风险。

临床相关性

当依靠质量可疑的骨内缝线锚钉固定时,我们建议考虑使用生物可吸收水泥增强缝线锚钉固定。这种方法还具有生物可吸收性的潜力,可能更适合关节镜应用。

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