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美国肥胖症、II 型糖尿病、高脂血症和高血压的流行情况:来自 GE Centricity 电子病历数据库的研究结果。

Prevalence of obesity, type II diabetes mellitus, hyperlipidemia, and hypertension in the United States: findings from the GE Centricity Electronic Medical Record database.

机构信息

Thomas Jefferson University School of Population Health, Philadelphia, Pennsylvania 19107, USA.

出版信息

Popul Health Manag. 2010 Jun;13(3):151-61. doi: 10.1089/pop.2009.0039.

Abstract

This study analyzed GE Centricity Electronic Medical Record (EMR) data to examine the effects of body mass index (BMI) and obesity, key risk factor components of metabolic syndrome, on the prevalence of 3 chronic diseases: type II diabetes mellitus, hyperlipidemia, and hypertension. These chronic diseases occur with high prevalence and impose high disease burdens. The rationale for using Centricity EMR data is 2-fold. First, EMRs may be a good source of BMI/obesity data, which are often underreported in surveys and administrative databases. Second, EMRs provide an ideal means to track variables over time and, thus, allow longitudinal analyses of relationships between risk factors and disease prevalence and progression. Analysis of Centricity EMR data showed associations of age, sex, race/ethnicity, and BMI with diagnosed prevalence of the 3 conditions. Results include uniform direct correlations between age and BMI and prevalence of each disease; uniformly greater disease prevalence for males than females; varying differences by race/ethnicity (ie, African Americans have the highest prevalence of diagnosed type II diabetes and hypertension, while whites have the highest prevalence of diagnosed hypertension); and adverse effects of comorbidities. The direct associations between BMI and disease prevalence are consistent for males and females and across all racial/ethnic groups. The results reported herein contribute to the growing literature about the adverse effects of obesity on chronic disease prevalence and about the potential value of EMR data to elucidate trends in disease prevalence and facilitate longitudinal analyses.

摘要

本研究分析了通用电气公司的 Centricity 电子病历 (EMR) 数据,以研究体重指数 (BMI) 和肥胖作为代谢综合征的关键风险因素对三种慢性疾病(II 型糖尿病、高脂血症和高血压)的患病率的影响。这些慢性病的患病率较高,疾病负担较重。使用 Centricity EMR 数据的理由有两个。首先,EMR 可能是 BMI/肥胖数据的良好来源,而这些数据在调查和行政数据库中往往报告不足。其次,EMR 提供了一个随时间跟踪变量的理想手段,因此可以对危险因素与疾病的患病率和进展之间的关系进行纵向分析。对 Centricity EMR 数据的分析表明,年龄、性别、种族/民族和 BMI 与三种疾病的诊断患病率有关。分析结果包括年龄和 BMI 与每种疾病的患病率之间呈一致的正相关;男性的疾病患病率普遍高于女性;不同种族/民族之间存在差异(即,非裔美国人的 II 型糖尿病和高血压诊断患病率最高,而白人的高血压诊断患病率最高);以及合并症的不良影响。BMI 与疾病患病率之间的直接关联在男性和女性以及所有种族/民族群体中都是一致的。本报告的结果为肥胖对慢性病患病率的不良影响的日益增多的文献做出了贡献,并为 EMR 数据阐明疾病患病率趋势和促进纵向分析的潜在价值提供了依据。

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