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犬颅交叉韧带疾病:生物学与生物力学

Cranial cruciate ligament disease in dogs: biology versus biomechanics.

作者信息

Cook James L

机构信息

Comparative Orthopaedic Laboratory, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA.

出版信息

Vet Surg. 2010 Apr;39(3):270-7. doi: 10.1111/j.1532-950X.2010.00653.x.

DOI:10.1111/j.1532-950X.2010.00653.x
PMID:20522208
Abstract

The stifle joint of dogs is an organ comprised of multiple tissue types that must work in concert to maintain joint health and function. Cruciate disease in dogs is caused by a spectrum of causal and risk factors that result in a final common pathway of abnormal biomechanics and abnormal biology causing osteoarthritis, or organ failure, of the stifle and the clinical signs of lameness, pain, and limb dysfunction. It is vital to understand the components of the biologic and biomechanical pathologies to improve our understanding of cruciate disease in dogs so that we can improve preventative, diagnostic, and therapeutic strategies for our canine patients.

摘要

犬的 stifle 关节是一个由多种组织类型组成的器官,这些组织必须协同工作以维持关节的健康和功能。犬的十字韧带疾病由一系列因果和风险因素引起,这些因素导致了异常生物力学和异常生物学的最终共同途径,从而引起 stifle 的骨关节炎或器官衰竭,以及跛行、疼痛和肢体功能障碍的临床症状。了解生物和生物力学病理学的组成部分对于提高我们对犬十字韧带疾病的认识至关重要,这样我们就可以改进针对我们犬类患者的预防、诊断和治疗策略。

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