Rajanarendar Eligeti, Raju Samala, Siva Rami Reddy Atthunuri, Govardhan Reddy Kundur, Nagi Reddy Modugu
Department of Chemistry, Kakatiya University.
Chem Pharm Bull (Tokyo). 2010 Jun;58(6):833-9. doi: 10.1248/cpb.58.833.
We report a mild, fast, highly efficient and eco-friendly protocol for the green synthesis of pyrrolo[2,3-d]isoxazoles and a new series of novel benzyl bis-pyrrolo[2,3-d]isoxazoles from nitro styrylisoxazoles in SnCl(2)-ionic liquid by reductive cyclization. These reactions were performed at ambient temperature which resulted in good yields in short reaction time, without requiring any organic solvent and catalyst.
我们报道了一种温和、快速、高效且环保的方法,用于通过还原环化反应在SnCl(2)-离子液体中由硝基苯乙烯异恶唑绿色合成吡咯并[2,3-d]异恶唑以及一系列新型苄基双吡咯并[2,3-d]异恶唑。这些反应在室温下进行,反应时间短且产率良好,无需任何有机溶剂和催化剂。